Line tension of multicomponent bilayer membranes

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Ashkan DehghanAn-Chang Shi

Abstract

The line tension or edge energy of bilayer membranes self-assembled from binary amphiphilic molecules is studied using self-consistent-field theory (SCFT). Specifically, solutions of the SCFT equations corresponding to an infinite membrane with a circular pore, or an open membrane, are obtained for a coarse-grained model in which the amphiphilic species and hydrophilic solvents are represented by ABandED diblock copolymers and C homopolymers, respectively. The edge energy of the membrane is extracted from the free energy of the open membranes. Results for membranes composed of mixtures of symmetric and cone- or inverse cone-shaped amphiphilic molecules with neutral and/or repulsive interactions are obtained and analyzed. It is observed that an increase in the concentration of the cone-shaped species leads to a decrease of the line tension. In contrast, adding inverse cone-shaped copolymers results in an increase of the line tension. Furthermore, the density profile of the copolymers reveals that the line tension is regulated by the distribution of the amphiphiles at the bilayer edge.

References

Nov 1, 1973·Zeitschrift Für Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie·W Helfrich
Apr 8, 1993·Biochimica Et Biophysica Acta·D V Zhelev, D Needham
May 1, 1997·Biophysical Journal·J D Moroz, P Nelson
Feb 12, 1998·Biochimica Et Biophysica Acta·C KarolisK D Barrow
Apr 1, 1996·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·R R Netz, M Schick
Dec 12, 2001·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·R M RaphaelB Zeks
Mar 1, 2003·Biophysical Journal·Erdem KaratekinFrançoise Brochard-Wyart
Apr 12, 2003·Physical Review Letters·P-H PuechF Brochard-Wyart
Mar 9, 2004·Biochimica Et Biophysica Acta·Stanisława Koronkiewicz, Sławomir Kalinowski
Mar 26, 2004·Biophysical Journal·Hari LeontiadouSiewert J Marrink
Jul 9, 2004·Biophysical Journal·Frank Y JiangJames T Kindt
Aug 25, 2004·Biophysical Journal·K KatsovM Schick
Oct 29, 2005·The Journal of Chemical Physics·Zun-Jing Wang, Daan Frenkel
Jan 25, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Jason de JoannisJames T Kindt
May 6, 2006·The Journal of Chemical Physics·J WohlertW J Briels
Dec 2, 2009·The Journal of Chemical Physics·Wouter K den Otter
Jul 21, 2010·Biophysical Journal·Yuka SakumaMasayuki Imai
May 24, 2011·Physical Review Letters·Christina L TingZhen-Gang Wang
Mar 30, 2012·Biophysical Journal·Mingyang HuMarkus Deserno
Nov 13, 2012·PloS One·Anne-Florence BitbolJean-Baptiste Fournier
Jun 29, 2013·Faraday Discussions·John F Nagle
Aug 16, 2013·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Jianfeng LiJiajia Zhou
Jan 24, 2015·The Journal of Chemical Physics·H PeraF A M Leermakers

❮ Previous
Next ❯

Citations

Aug 11, 2020·The Journal of Chemical Physics·Mayank Dixit, Themis Lazaridis
Mar 11, 2016·Physical Chemistry Chemical Physics : PCCP·Nelli ErwinRoland Winter
Aug 14, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Yang YangXinghua Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
Jianfeng LiJiajia Zhou
Langmuir : the ACS Journal of Surfaces and Colloids
Martin J Greenall, Gerhard Gompper
The European Physical Journal. E, Soft Matter
A ImparatoR Lipowsky
© 2021 Meta ULC. All rights reserved