Lineage-specific loss of FGF17 within the avian orders Galliformes and Passeriformes

Gene
John Abramyan

Abstract

The genomic and developmental complexity of vertebrates is commonly attributed to two rounds of whole genome duplications which occurred at the base of the vertebrate radiation. These duplications led to the rise of several, multi-gene families of developmental proteins like the fibroblast growth factors (FGFs); a signaling protein family which functions at various stages of embryonic development. One of the major FGF assemblages arising from these duplications is the FGF8 subfamily, which includes FGF8, FGF17, and FGF18 in tetrapods. While FGF8 and FGF18 are found in all tetrapods and are critical for embryonic survival, genomic analyses suggest putative loss of FGF17 in various lineages ranging from frogs and fish, to the chicken. This study utilizes 27 avian genomes in conjunction with molecular analyses of chicken embryos to confirm the loss of FGF17 in chicken as a true, biological occurrence. FGF17 is also missing in the turkey, black grouse, Japanese quail and northern bobwhite genomes. These species, along with chicken, form a monophyletic clade in the order Galliformes. Four additional species, members of the clade Passeroidea, within the order Passeriformes, are also missing FGF17. Additionally, analysis of intact FGF...Continue Reading

References

Sep 21, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·S J Gould, R C Lewontin
Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Jul 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M Kimura, T Ohta
May 23, 1994·Proceedings. Biological Sciences·A L Hughes
Mar 1, 1993·Journal of Molecular Evolution·A L Hughes, M K Hughes
May 9, 1998·Proceedings of the National Academy of Sciences of the United States of America·J ZhangM Nei
Jun 25, 1999·Mechanisms of Development·J XuD M Ornitz
May 5, 2001·Genome Research·W Makalowski
Apr 9, 2002·Genes & Development·Zhonghao LiuDavid M Ornitz
Aug 15, 2002·Trends in Genetics : TIG·Austin L Hughes
Oct 12, 2004·Trends in Genetics : TIG·Nobuyuki Itoh, David M Ornitz
Dec 14, 2004·Nature·UNKNOWN International Chicken Genome Sequencing Consortium
Jul 15, 2005·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Cornel PopoviciDaniel Birnbaum
Dec 13, 2005·Nature Reviews. Genetics·Jordi Garcia-Fernàndez
Oct 28, 2006·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·John H Postlethwait
Dec 7, 2006·Biology Letters·Per G P EricsonGerald Mayr
May 8, 2007·Molecular Biology and Evolution·Ziheng Yang
Nov 17, 2007·Nature Reviews. Genetics·Cristian CañestroJohn H Postlethwait
Jun 11, 2008·BMC Evolutionary Biology·Karl R WottonKatharine E Lewis
Jun 28, 2008·Science·Shannon J HackettTamaki Yuri
Sep 9, 2008·BMC Evolutionary Biology·Jean-Yves SireMarc Girondot
Nov 19, 2008·Nature Reviews. Genetics·Gavin C Conant, Kenneth H Wolfe
Jan 21, 2009·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Jeffery P Demuth, Matthew W Hahn
Jun 30, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Richard JovelinJohn H Postlethwait
Jul 15, 2009·The Journal of Heredity·Matthew W Hahn
Aug 5, 2009·Nature Reviews. Genetics·Yves Van de PeerAxel Meyer
Aug 5, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·John AbramyanPeter Koopman
May 4, 2010·The Journal of Comparative Neurology·Hassan MarzbanRichard Hawkes
Oct 21, 2010·Cellular Signalling·Beth BragdonAnja Nohe
Jun 24, 2011·Genome Biology and Evolution·Federico G HoffmannJay F Storz
Aug 25, 2011·Nature Communications·Alexander SuhJürgen Schmitz
Oct 19, 2011·Nature Reviews. Genetics·Rowan D H Barrett, Hopi E Hoekstra
Mar 1, 2012·Molecular Biology and Evolution·Alexei J DrummondAndrew Rambaut
Nov 16, 2012·Nature Reviews. Molecular Cell Biology·Christof Niehrs
Nov 30, 2012·Nucleic Acids Research·Dennis A BensonEric W Sayers
Jan 8, 2013·Seminars in Cell & Developmental Biology·Cristian CañestroJordi Garcia-Fernàndez
Jan 25, 2013·BMC Evolutionary Biology·Robert W MeredithMark S Springer

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Citations

Jan 29, 2016·Development, Growth & Differentiation·Shigehiro KurakuYuichiro Hara
Feb 28, 2017·Scientific Reports·Cedric PattheySara Ivy Wilson
Dec 23, 2017·Reproduction : the Official Journal of the Society for the Study of Fertility·Anthony Estienne, Christopher A Price

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