Linear pattern of West Nile virus-associated chorioretinitis is related to retinal nerve fibres organization

Eye
Moncef KhairallahRiadh Messaoud

Abstract

To clarify the reason for the linear pattern of West Nile virus (WNV)-associated chorioretinitis. The study included 12 patients (24 eyes) with WNV-associated chorioretinitis. All the patients underwent a complete ophthalmic evaluation, including dilated fundus examination, fundus photography, fluorescein angiography, and indocyanine green angiography. Characteristics of linear streaks, particularly their relationship to the course of retinal and choroidal vessels, and pattern of retinal nerve fibres, were analysed. All patients had bilateral multifocal chorioretinitis with linear clustering of chorioretinal lesions associated with a variable number of scattered lesions. Linear streaks, variable in number and length, originated from the optic disc or its vicinity in most cases. Their course in all cases appeared to closely follow the course of retinal nerve fibres, rather than that of retinal or choroidal vessels. Results of our study show that the linear pattern of WNV-associated chorioretinitis is related to retinal nerve fibres organization, suggesting a contiguous spread of WNV virus from central nerve system via the optic nerve fibres to the outer retina, retinal pigment epithelium, and choroid.

References

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Citations

Apr 13, 2012·Obstetrical & Gynecological Survey·Nina M RoosGerda G Zeeman
Aug 28, 2009·International Ophthalmology·Moncef KhairallahVenu Nadella
Apr 9, 2010·International Ophthalmology Clinics·Moncef KhairallahSonia Attia
Dec 10, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·U PleyerM M Nentwich
May 7, 2013·Ophthalmology·Rathinam R SivakumarManmohan Parida
Nov 5, 2011·Veterinary Ophthalmology·Rachel L MathesKathern E Myrna
Nov 22, 2011·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Jyoti ShuklaManmohan Parida
Dec 22, 2012·Ophthalmic Research·Moncef KhairallahRiadh Messaoud
Oct 28, 2016·Japanese Journal of Ophthalmology·Manabu MochizukiHiroshi Takase
Nov 4, 2016·The American Journal of Tropical Medicine and Hygiene·Bradley J BlitvichMark A Greiner
Dec 26, 2016·Survey of Ophthalmology·Joanne H LeeRupesh Agrawal
Feb 23, 2019·Ocular Immunology and Inflammation·Moncef KhairallahEmmett T Cunningham
Sep 14, 2013·Current Opinion in Ophthalmology·Moncef Khairallah, Rim Kahloun
Oct 23, 2014·Retina·Daniel LearnedGeorge A Williams
Aug 23, 2020·Indian Journal of Ophthalmology·Padmamalini MahendradasMoncef Khairallah
Jan 1, 2017·Mediators of Inflammation·Jillian M CarrJustine R Smith
Dec 20, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Alessandro MarcheseMaurizio Battaglia Parodi
Nov 13, 2019·Journal of Neurovirology·Lindsey RearighSara H Bares
Mar 3, 2015·International Ophthalmology Clinics·Daniel B ConnorsSteven Yeh
Nov 6, 2020·Vaccines·Antoine RousseauMarc Labetoulle
Jul 21, 2021·Ocular Immunology and Inflammation·Jamie M Nord, Naomi R Goldberg

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