Linezolid-associated peripheral neuropathy

Mayo Clinic Proceedings
Jennifer P RhoRobert T Trousdale

Abstract

Linezolid is the first drug in a new class of synthetic antimicrobials, the oxazolidinones, to be approved by the Food and Drug Administration. Linezolid is active against methicillin- and vancomycin-resistant gram-positive microorganisms. We describe 2 patients who developed peripheral neuropathy after prolonged treatment with linezolid. Linezolid-associated peripheral neuropathy has not been well documented. Most reported cases of linezolid-associated peripheral neuropathy have occurred in patients who took linezolid for a period longer than the recommended 28 or fewer days. Health care providers must be alert to the potential for serious adverse effects associated with linezolid use, including peripheral neuropathy.

Citations

Nov 22, 2005·The British Journal of Ophthalmology·K Kulkarni, L V Del Priore
Nov 30, 2005·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G M Eliopoulos
Jan 1, 2009·The Pediatric Infectious Disease Journal·W Matthew LinamMichael A Gerber
Jul 1, 2008·Expert Review of Clinical Pharmacology·Tina Q Tan, Ram Yogev
Oct 25, 2017·Clinical Pharmacokinetics·Claire RogerLaurent Muller
May 25, 2005·The Journal of Antimicrobial Chemotherapy·Jesús FortúnSantiago Moreno
Jun 15, 2006·Expert Review of Anti-infective Therapy·William J Peppard, John A Weigelt
Apr 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·An S De VrieseJohan R Boelaert
Sep 6, 2007·The Annals of Pharmacotherapy·Tomasz Z JodlowskiJohn Conry
May 6, 2011·The Journal of Antimicrobial Chemotherapy·F Kate Gould
Dec 17, 2008·Current Neurology and Neuroscience Reports·Louis H Weimer, Noor Sachdev
Sep 28, 2013·The Journal of Antimicrobial Chemotherapy·Baek-Nam KimMyoung-Don Oh
Dec 12, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Douglas R OsmonUNKNOWN Infectious Diseases Society of America
Nov 2, 2014·The Neurohospitalist·Kate T Brizzi, Jennifer L Lyons
Mar 14, 2020·Critical Care Explorations·Abdullah M PervaizMelissa Mercado
Dec 5, 2008·Expert Review of Anti-infective Therapy·David J HerrmannBryan J Buechel
Mar 10, 2005·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Steven H McKinley, Rod Foroozan
Aug 14, 2018·Internal Medicine·Seul LeeChoonhee Son
Jan 14, 2020·Case Reports in Critical Care·Rashmi MishraTrupti Vakde
Jan 8, 2016·American Journal of Therapeutics·Venugopalan Y VishnuVivek Lal
Sep 28, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J R LentinoV L Yu
Oct 12, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Ana Dioun BroylesMariana Castells
Nov 22, 2005·Infectious Disease Clinics of North America·Irene G SiaAdolf W Karchmer
Sep 22, 2009·The Journal of Infection·Donald C Vinh, Ethan Rubinstein

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