Linezolid-associated toxic optic neuropathy

Neurology
J C RuckerM S Lee

Abstract

The oxazolidinone antimicrobial linezolid is effective against gram-positive bacteria. Although maximal recommended therapy is 28 days, treatment durations greater than this are common. Linezolid may cause reversible optic neuropathy and irreversible peripheral neuropathy after months of treatment. Three cases of linezolid-induced optic and peripheral neuropathy are described, and previously reported cases of linezolid-induced optic neuropathy are reviewed. The mechanism of neural toxicity may be impairment of mitochondrial protein synthesis.

Citations

Apr 6, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A SorianoJ Mensa
Sep 19, 2009·Japanese Journal of Ophthalmology·Katsuji KiuchiSanae Wada
Dec 17, 2008·Current Neurology and Neuroscience Reports·Louis H Weimer, Noor Sachdev
Sep 20, 2011·The American Journal of Clinical Hypnosis·Daniel P Kohen
Jan 1, 2009·The Pediatric Infectious Disease Journal·W Matthew LinamMichael A Gerber
May 18, 2013·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Michelle Y Wang, Alfredo A Sadun
Aug 6, 2013·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Jinu HanSueng Han Han
Dec 21, 2006·The British Journal of Ophthalmology·M JavaheriA A Sadun
Jul 13, 2012·Infection and Drug Resistance·Sally Ager, Kate Gould
Oct 15, 2014·Current Opinion in Infectious Diseases·Pranita D Tamma, Alice J Hsu
Oct 29, 2014·Current Infectious Disease Reports·Shamik BhattacharyyaAaron L Berkowitz
Nov 12, 2009·Infection·S EspositoUNKNOWN Bone Joint Infections Committee for the Italian Society of Infectious Tropical Diseases (SIMIT)
Oct 9, 2013·Current Opinion in Ophthalmology·Ugur E Altiparmak
Sep 13, 2011·Expert Review of Anti-infective Therapy·Javier Cobo, Jose Luis Del Pozo
May 16, 2009·Expert Opinion on Therapeutic Patents·Oludotun A Phillips, Leyla H Sharaf
Feb 6, 2014·Expert Review of Clinical Pharmacology·Eric BeresfordH David Friedland
Jul 1, 2008·Expert Review of Clinical Pharmacology·Tina Q Tan, Ram Yogev
Dec 3, 2015·Expert Opinion on Drug Safety·Geehan Suleyman, Marcus J Zervos
Feb 14, 2016·International Ophthalmology·Nobuhito IshiiAkitoshi Yoshida
Jul 19, 2012·Expert Opinion on Drug Metabolism & Toxicology·Mitan R GokulgandhiAshim K Mitra
Jan 26, 2008·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Junping LiBrenda J Tripathi
Nov 28, 2015·The Journal of Antimicrobial Chemotherapy·Ilja BobylevHelmar C Lehmann
Aug 5, 2011·Survey of Ophthalmology·Margherita E Eschle-MeniconiThomas J Wolfensberger
Jan 1, 2009·Journal of Infection and Public Health·K BanwanV O Rotimi
Jun 19, 2007·Diagnostic Microbiology and Infectious Disease·Nalini Rao, Cindy W Hamilton
Sep 26, 2006·Pharmacoepidemiology and Drug Safety·Leonard AzamfireiCristina Berteanu
Aug 29, 2006·Seminars in Pediatric Infectious Diseases·Karina M Butler
Nov 30, 2010·Progress in Retinal and Eye Research·Patrick Yu-Wai-ManPatrick F Chinnery
Dec 3, 2014·Clinical Therapeutics·Arun Mattappalil, Kari A Mergenhagen
Apr 4, 2014·Journal of Medicinal Chemistry·Mikhail F Gordeev, Zhengyu Y Yuan
Jul 25, 2018·Current Eye Research·Jeffrey J YuChantal J Boisvert
Sep 6, 2018·Neural Computation·Beatrice Alexandra Golomb
Jul 20, 2019·CNS Drugs·Madison K Bangert, Rodrigo Hasbun
Feb 1, 2011·European Journal of Ophthalmology·Tamara L BerezinaRobert D Fechtner
Aug 14, 2018·Internal Medicine·Seul LeeChoonhee Son
Sep 22, 2009·The Journal of Infection·Donald C Vinh, Ethan Rubinstein

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