Lingual Pressure Dysfunction Contributes to Reduced Swallowing-Related Quality of Life in Parkinson's Disease

Journal of Speech, Language, and Hearing Research : JSLHR
Laura L PittsLeora R Cherney

Abstract

Purpose Dysphagia in Parkinson's disease (PD) is a major cause of depression and reduced quality of life (QOL). PD-related dysphagia often involves lingual dysfunction and weak pressure generation. The relation of disordered lingual pressure generation to swallowing-related QOL in persons with PD remains unknown. Method Twenty-four persons with idiopathic PD completed the Swallowing Quality of Life (SWAL-QOL) questionnaire and an evaluation of anterior and posterior tongue strength. Peak pressures were compared to age- and sex-matched controls. The magnitude of and latency to peak pressure were explored in relation to SWAL-QOL scores. Results Persons with PD exhibited significant anterior (p = .019) but not posterior (p = .081) lingual weakness compared to controls. Persons with PD and reduced anterior tongue strength (< 42 kPa) reported lower SWAL-QOL total (p = .043), extended eating durations (p = .025), and a reduced desire to eat (p = .020). Prolonged latency to peak anterior pressure in PD inversely correlated with SWAL-QOL total (r = -.750, p < .001) and served as a significant, independent predictor of 67% of the variance in SWAL-QOL total when controlling for age, sex, and disease stage. Conclusion Overall, SWAL-QOL sc...Continue Reading

References

May 1, 1967·Neurology·M M Hoehn, M D Yahr
Feb 11, 2000·Journal of Speech, Language, and Hearing Research : JSLHR·N P SolomonE S Luschei
Oct 24, 2001·Brain : a Journal of Neurology·A BerardelliM Hallett
Sep 17, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Christopher G GoetzUNKNOWN Movement Disorder Society Task Force on Rating Scales for Parkinson's Disease
Apr 21, 2005·Journal of Chemical Ecology·Astrid T GrootCoby Schal
Aug 9, 2005·Archives of Physical Medicine and Rehabilitation·Michael A CraryMichael E Groher
Oct 19, 2006·Age and Ageing·Nick MillerDavid Burn
Mar 14, 2007·Parkinsonism & Related Disorders·Tjalf Ziemssen, Heinz Reichmann
May 9, 2009·Movement Disorders : Official Journal of the Movement Disorder Society·Emily K Plowman-PrineJohn C Rosenbek
Feb 16, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Bernardo RodriguesAilton Melo
May 5, 2011·Movement Disorders : Official Journal of the Movement Disorder Society·Pascal H H M Van LieshoutAnthony E Lang
Dec 6, 2011·Parkinsonism & Related Disorders·J G KalfM Munneke
Jan 11, 2012·Journal of Speech, Language, and Hearing Research : JSLHR·Laura L GingrichLeonard L LaPointe
Jul 23, 2013·NeuroRehabilitation·Natalie ArgoloAna Caline Nóbrega
May 13, 2014·Archives of Physical Medicine and Rehabilitation·Ruvini P AthukoralaMaggie-Lee Huckabee
Jun 24, 2014·Dysphagia·Danielle CarneiroOtávio Gomes Lins
Nov 26, 2015·The Annals of Otology, Rhinology, and Laryngology·Julia K EllerstonKatherine A Kendall
Jul 9, 2017·Dysphagia·Laura L PittsLeonard L LaPointe
Feb 6, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Laura L PittsJulie A G Stierwalt
Jun 15, 2018·Brain : a Journal of Neurology·Matteo BolognaAlfredo Berardelli

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