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Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations

Science

May 20, 1994

D G MarshT H Beaty

Abstract

Sib-pair analysis of 170 individuals from 11 Amish families revealed evidence for linkage of five markers in chromosome 5q31.1 with a gene controlling total serum immunoglobulin E (IgE) concentration. No linkage was found between these markers and specific IgE antibody concentrations. A...read more

Mentioned in this Paper

Likelihood Functions
Immediate Hypersensitivity
IL4 wt Allele
Lod Score
Genetic Markers
Allergens
Immunoglobulin E
Teens
Chromosomes, Human, Pair 5
Genes, vif
45
Paper Details
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Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations

Science

May 20, 1994

D G MarshT H Beaty

PMID: 8178175

DOI: 10.1126/science.8178175

Abstract

Sib-pair analysis of 170 individuals from 11 Amish families revealed evidence for linkage of five markers in chromosome 5q31.1 with a gene controlling total serum immunoglobulin E (IgE) concentration. No linkage was found between these markers and specific IgE antibody concentrations. A...read more

Mentioned in this Paper

Likelihood Functions
Immediate Hypersensitivity
IL4 wt Allele
Lod Score
Genetic Markers
Allergens
Immunoglobulin E
Teens
Chromosomes, Human, Pair 5
Genes, vif
45

Similar Papers Found In These Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

General Biology Journal eTOCs

Discover the latest general biology research in this collection of the top biology journals.

Related Papers

The New England Journal of Medicine

Genetic susceptibility to asthma--bronchial hyperresponsiveness coinherited with a major gene for atopy

The New England Journal of MedicineOctober 5, 1995
D S PostmaR C Levitt
Genomics

Evidence for a locus regulating total serum IgE levels mapping to chromosome 5

GenomicsSeptember 15, 1994
Deborah A MeyersEugene R Bleecker
Paper Details
References
  • References
  • Citations488
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations488
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