Linkage to care, mobility and retention of HIV-positive postpartum women in antiretroviral therapy services in South Africa

Journal of the International AIDS Society
Tamsin K PhillipsLandon Myer

Abstract

Linkage to care and mobility postpartum present challenges to long-term retention after initiating antiretroviral therapy (ART) in pregnancy, but there are few insights from sub-Saharan Africa. We aimed to describe postpartum linkage to care, mobility, retention and viral suppression after ART initiation in pregnancy. Using routine electronic data we assessed HIV-specific health contacts and clinic movements among women initiating ART in an integrated antenatal care (ANC) and ART clinic in Cape Town, South Africa. The local care model includes mandatory transfer to general ART clinics postpartum. We investigated linkage to care after leaving the integrated clinic and mobility to new clinics until 30 months on ART. We used Poisson regression to explore predictors of linkage, retention (accessing care at least once at both 12 [6 to <18] and 24 [18 to <30] months on ART), and viral suppression (HIV viral load [VL] ≤50 and ≤1000 copies/mL after 12 months on ART). Among 617 women, 23% never linked to care; 71% and 65% were retained at 12 and 24 months on ART respectively, with 59% retained in care at both times. Those who linked (n = 485) accessed HIV care at 98 different clinics and 21% attended ≥2 clinics. Women >25 years, married...Continue Reading

References

Mar 23, 2004·American Journal of Epidemiology·Guangyong Zou
Mar 1, 2006·Sexually Transmitted Diseases·Heidi W ReynoldsLaura Johnson
Mar 3, 2007·Obstetrics and Gynecology·A P MohllajeeP A Marchbanks
Oct 21, 2010·Tropical Medicine & International Health : TM & IH·Kevin D DeaneDeborah Johnston
May 21, 2011·The Mount Sinai Journal of Medicine, New York·Barbara S TaylorJennifer Hirsch
Nov 1, 2011·PLoS Medicine·Benjamin H ChiUNKNOWN International Epidemiologic Databases to Evaluate AIDS Collaboration
Jun 20, 2012·The Journal of Infectious Diseases·Jason R AndrewsRochelle P Walensky
May 2, 2014·Journal of the International AIDS Society·Meg OslerAndrew Boulle
Aug 5, 2014·Tropical Medicine & International Health : TM & IH·Hannock TweyaSam Phiri
Feb 28, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Landon MyerElaine J Abrams
May 6, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Matthew P Fox, Sydney Rosen
Sep 10, 2015·Current Opinion in HIV and AIDS·Frank TanserAdrian Dobra
Jan 23, 2016·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·Joanne Elizabeth PeterYogan Pillay
Jan 23, 2016·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·Helen L WallsJohanna Hanefeld
Apr 22, 2016·Tropical Medicine & International Health : TM & IH·Lynne WilkinsonAnna Grimsrud
Apr 28, 2016·Journal of the International AIDS Society·Pascal GeldsetzerTill Bärnighausen
May 22, 2016·Tropical Medicine & International Health : TM & IH·Jara Llenas-GarcíaUNKNOWN SolidarMed and IeDEA-Southern Africa
Jun 30, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Landon MyerElaine J Abrams
Dec 9, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Landon MyerElaine J Abrams
Feb 23, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kate ClouseMatthew P Fox

❮ Previous
Next ❯

Citations

Apr 28, 2020·AIDS Care·Ana Clara Cruz ZonenscheinMarcos Augusto Bastos Dias
Jun 13, 2019·BMC Public Health·Elizabeth SpoonerAnna Coutsoudis
Jul 22, 2018·Journal of the International AIDS Society·Susan CasselsJanet Seeley
Apr 2, 2020·International Journal of Environmental Research and Public Health·Petal Petersen WilliamsBronwyn Myers
Aug 18, 2020·The Pediatric Infectious Disease Journal·Elri du PlooyHelena Rabie
Mar 22, 2019·Infectious Diseases in Obstetrics and Gynecology·Christina M MeadeAnandi N Sheth
Jul 22, 2018·Journal of the International AIDS Society·Carol S CamlinJanet Seeley
Nov 8, 2020·Tropical Medicine & International Health : TM & IH·Phepo MogobaLandon Myer
Apr 6, 2021·International Quarterly of Community Health Education·Nosipho ShangaseAudrey Pettifor
Apr 30, 2021·AIDS Research and Human Retroviruses·Emily KoechSylvia Ojoo
May 6, 2021·Current HIV/AIDS Reports·Aaloke ModyElvin H Geng
May 23, 2021·Journal of the International AIDS Society·Nathaniel T YohannesPeter F Rebeiro

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT01933477

Software Mentioned

STATA
ArcMap

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.