Linking sub-cellular biomarkers to embryo aberrations in the benthic amphipod Monoporeia affinis

Aquatic Toxicology
Martin Reutgard, Sara Furuhagen

Abstract

To adequately assess and monitor environmental status in the aquatic environment a broad approach is needed that integrates physical variables, chemical analyses and biological effects at different levels of the biological organization. Embryo aberrations in the Baltic Sea key species Monoporeia affinis can be induced by both metals and organic substances as well as by hypoxia, increasing temperatures and malnutrition. This amphipod has therefore been used for more than three decades as a biological effect indicator in monitoring and assessment of chemical pollution and environmental stress. However, little is known about the sub-cellular mechanisms underlying embryo aberrations. An improved mechanistic understanding may open up the possibility of including sub-cellular alterations as sensitive warning signals of stress-induced embryo aberrations. In the present study, M. affinis was exposed in microcosms to 4 different sediments from the Baltic Sea. After 88-95 days of exposure, survival and fecundity were determined as well as the frequency and type of embryo aberrations. Moreover, oxygen radical absorption capacity (ORAC) was assayed as a proxy for antioxidant defense, thiobarbituric acid reactive substances (TBARS) level as...Continue Reading

References

Jan 21, 2000·Free Radical Biology & Medicine·R L Prior, G Cao
Jan 1, 2003·Neuroscience Research·Joana Barbosa MeloCatarina Resende Oliveira
Dec 29, 2004·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Carlos BarataCinta Porte
May 12, 2005·Journal of Agricultural and Food Chemistry·Ronald L PriorKaren Schaich
Jun 7, 2005·Marine Pollution Bulletin·Ann-Kristin Eriksson Wiklund, Brita Sundelin Dag Broman
Jan 13, 2006·Ecotoxicology and Environmental Safety·Athanasios ValavanidisMichael Scoullos
Sep 19, 2006·The International Journal of Biochemistry & Cell Biology·Marian ValkoJoshua Telser
May 16, 2008·Biometrical Journal. Biometrische Zeitschrift·Torsten HothornPeter Westfall
Jan 8, 2009·Toxicological Sciences : an Official Journal of the Society of Toxicology·Peter G WellsAndrea W Wong
May 2, 2009·Marine Pollution Bulletin·J K H FangP K S Shin
Jun 9, 2009·Free Radical Biology & Medicine·Etsuo Niki
Sep 8, 2010·Environmental Toxicology and Chemistry·Gerald T AnkleyDaniel L Villeneuve
Nov 16, 2010·Aquatic Toxicology·Volodymyr I Lushchak
Feb 1, 2003·Environmental Toxicology and Pharmacology·Ron van der OostNico P E Vermeulen
Sep 1, 1994·Ecotoxicology·M H Depledge, M C Fossi
Apr 5, 2014·PloS One·Ann-Kristin Eriksson WiklundElena Gorokhova
Sep 24, 2014·Environmental Science & Technology·Sara FuruhagenElena Gorokhova

❮ Previous
Next ❯

Citations

Mar 9, 2018·Royal Society Open Science·Agnes M L KarlsonElena Gorokhova

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.