Linking transcriptional responses to organismal tolerance reveals mechanisms of thermal sensitivity in a mesothermal endangered fish

Molecular Ecology
Lisa M KomoroskeNann A Fangue

Abstract

Forecasting species' responses to climate change requires understanding the underlying mechanisms governing environmental stress tolerance, including acclimation capacity and acute stress responses. Current knowledge of these physiological processes in aquatic ectotherms is largely drawn from eurythermal or extreme stenothermal species. Yet many species of conservation concern exhibit tolerance windows and acclimation capacities in between these extremes. We linked transcriptome profiles to organismal tolerance in a mesothermal endangered fish, the delta smelt (Hypomesus transpacificus), to quantify the cellular processes, sublethal thresholds and effects of thermal acclimation on acute stress responses. Delta smelt initiated rapid molecular changes in line with expectations of theoretical thermal limitation models, but also exhibited diminished capacity to modify the expression of some genes and cellular mechanisms key to coping with acute thermal stress found in eurytherms. Sublethal critical thresholds occurred 4-6 °C below their upper tolerance limits, and thermal acclimation shifted the onset of acute thermal stress and tolerance as predicted. However, we found evidence that delta smelt's limited thermal plasticity may be ...Continue Reading

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Citations

Sep 9, 2016·Evolutionary Applications·Lisa M KomoroskeNann A Fangue
Jul 18, 2016·Trends in Biotechnology·Richard T Corlett
Oct 31, 2016·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Yueyang ZhangJames D Kieffer
Jun 3, 2016·The Journal of Experimental Biology·Ken M JeffriesNann A Fangue
Jun 16, 2017·Evolutionary Applications·Kyle W Wellband, Daniel D Heath
Oct 18, 2018·BMC Genomics·Arash AkbarzadehKristina M Miller
Jul 11, 2020·Proceedings of the National Academy of Sciences of the United States of America·Jonathan Sandoval-CastilloLuciano B Beheregaray
Jan 31, 2018·The Journal of Experimental Biology·Richard E ConnonNann A Fangue
Aug 13, 2021·The Journal of Experimental Biology·Theresa E MackeyKen M Jeffries

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