Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences

Veterinary Immunology and Immunopathology
M MaasV P M G Rutten

Abstract

Cloning and sequencing of the full length lion and cheetah interferon-gamma (IFN-gamma) transcript will enable the expression of the recombinant cytokine, to be used for production of monoclonal antibodies and to set up lion and cheetah-specific IFN-gamma ELISAs. These are relevant in blood-based diagnosis of bovine tuberculosis, an important threat to lions in the Kruger National Park. Alignment of nucleotide and amino acid sequences of lion and cheetah and that of domestic cats showed homologies of 97-100%.

References

Dec 1, 1993·The Journal of Experimental Medicine·J L FlynnB R Bloom
Jan 1, 1995·Immunogenetics·V E SchijnsR J de Groot
Mar 24, 2006·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Robert M KirbergerWencke M Wagner
May 20, 2008·Veterinary Immunology and Immunopathology·Shelley G RhodesKeith Jahans

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Citations

Jun 10, 2015·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Ashley D FranklinZhengguo Xiao

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