Lipase-Catalyzed Synthesis of Furan-Based Oligoesters and their Self-Assembly-Assisted Polymerization

ChemSusChem
Kumarasamy MuthusamySubbiah Nagarajan

Abstract

We investigate the synthesis of bio-based hydrophilic and hydrophobic oligoesters, which in turn are derived from easily accessible monomers from natural resources. In addition to the selection of renewable monomers, Novozyme 435, an immobilized lipase B from Candida antarctica was used for the oligomerization of monomers. The reaction conditions for oligomerization using Novozyme 435 were established to obtain a moderate-to-good yield. The average number of repeating units and the molecular weight distribution of hydrophilic and hydrophobic oligoester were identified by using NMR spectroscopy, gel-permeation chromatography, and MS. The oligoester derived from a hydrophilic monomer self-assembled to form a viscous solution, which upon further heating resulted in the formation of a polymer by the intermolecular Diels-Alder reaction. The viscosity of the solution and the assembly of oligoester to form a fibrous structure were investigated by using rheological studies, XRD, and SEM. The molecular weight of the cross-linked polymer was identified by using matrix-assisted laser desorption/ionization-MS. The thermal properties of the bio-based polymers were investigated by using thermogravimetric analysis and differential scanning ca...Continue Reading

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Citations

Oct 1, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Ayyapillai ThamizhanbanSubbiah Nagarajan
Dec 8, 2020·Journal of Agricultural and Food Chemistry·Ayyapillai ThamizhanbanSubbiah Nagarajan

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