Lipases: Valuable catalysts for dynamic kinetic resolutions

Biotechnology Advances
Amanda S de MirandaRodrigo O M A de Souza

Abstract

Dynamic kinetic resolutions have proven to be a useful method for the preparation of enantiopure compounds from racemates, leading to the formation of a single enantiomer in theoretically 100% yield. Because lipases are ubiquitous, versatile, stereoselective and robust biocatalysts, they have been successfully applied as co-catalysts in these reactions, being mostly combined with metals in the chemoenzymatic dynamic kinetic resolutions of alcohols and amines.

References

May 11, 2000·Organic Letters·F F HuertaJ E Backvall
Apr 3, 2001·Current Opinion in Chemical Biology·J D Stewart
Oct 25, 2001·The Journal of Organic Chemistry·Yoon Kyung ChoiMahn-Joo Kim
Aug 14, 2003·Chemical Reviews·Oscar Pàmies, Jan-E Bäckvall
Mar 24, 2004·Trends in Biotechnology·Oscar Pàmies, Jan-E Bäckvall
Mar 12, 2005·The Journal of Organic Chemistry·John LimantoR P Volante
May 26, 2005·Journal of the American Chemical Society·Yasuhisa Asano, Shigenori Yamaguchi
Oct 26, 2005·Chemical Communications : Chem Comm·Andrei ParvulescuPierre Jacobs
Nov 5, 2005·The Journal of Organic Chemistry·Peter OdmanUwe T Bornscheuer
Dec 15, 2005·Journal of the American Chemical Society·Jens Paetzold, Jan E Bäckvall
Feb 28, 2006·Angewandte Chemie·Iris HilkerAndreas Heise
Jun 24, 2006·Analytical Chemistry·Alain Berthod
Aug 12, 2006·The Journal of Organic Chemistry·Ann-Britt L FranssonJan-E Bäckvall
Sep 5, 2006·Angewandte Chemie·Albrecht BerkesselThomas N Müller
Sep 9, 2006·The Journal of Organic Chemistry·Stéphanie EscoubetMichèle P Bertrand
Sep 26, 2006·The Journal of Organic Chemistry·Pilar HoyosAndrés R Alcántara
Dec 8, 2006·Chemistry : a European Journal·Andrei N ParvulescuDirk E De Vos
Mar 14, 2007·Current Opinion in Chemical Biology·Belén Martín-Matute, Jan-E Bäckvall
Jul 14, 2007·Applied Microbiology and Biotechnology·Bettina M NestlKurt Faber
Jul 20, 2007·Chemistry : a European Journal·Christian C GruberWolfgang Kroutil
Aug 19, 2007·The Journal of Organic Chemistry·Soo-Byung KoJaiwook Park
Oct 25, 2007·Organic Letters·Jakob NorinderJan-E Bäckvall
Dec 22, 2007·Beilstein Journal of Organic Chemistry·Krisztián BogárJan-E Bäckvall
Jul 26, 2008·Chirality·Azlina Harun KamaruddinHairul Nazirah Abdul Halim
Apr 1, 2009·The Journal of Organic Chemistry·Fulvia FellugaFabio Benedetti

❮ Previous
Next ❯

Citations

Dec 30, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Denisa LeonteFlorin Dan Irimie
Feb 2, 2016·Enzyme and Microbial Technology·Ashwini C MathpatiBhalchandra M Bhanage
Dec 23, 2015·International Journal of Molecular Sciences·Ana Caroline Lustosa de Melo CarvalhoImmacolata Serra
Mar 19, 2016·Chemical Communications : Chem Comm·Yan ZhangOlof Ramström
Jul 26, 2017·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Michal TupecIva Pichová
Nov 22, 2018·Preparative Biochemistry & Biotechnology·Ayesha SadafSunil K Khare
Nov 1, 2017·Biotechnology Progress·Nipon SarmahC Sumana
Dec 28, 2019·International Journal of Molecular Sciences·Ly Thi Huong Luu LeT Doohun Kim
Feb 11, 2020·Chemical Communications : Chem Comm·Franziska KühnHarald Gröger
Nov 17, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Evelin Sánta-BellLászló Poppe
Jun 20, 2020·Angewandte Chemie·Shuke WuUwe T Bornscheuer
May 26, 2017·Angewandte Chemie·Nina G SchmidtWolfgang Kroutil
Oct 8, 2020·Applied Biochemistry and Biotechnology·Gülcan CoşkunÜlkü Mehmetoğlu
Mar 6, 2021·International Journal of Biological Macromolecules·F Rafiee, M Rezaee
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mónica RuizRoberto Fernandez-Lafuente
Aug 5, 2021·ACS Central Science·Joshua B PyserAlison R H Narayan
Dec 14, 2018·Organic Letters·Emese FarkasLászló Poppe
Aug 30, 2021·Biotechnology Advances·Rafael C RodriguesRoberto Fernandez-Lafuente

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Anti-Arrhythmic Drug Therapies

Anti-arrhythmic drugs are used to prevent abnormal heart rhythms. These medications are used in conditions including, ventricular tachycardia, ventricular fibrillation and atrial fibrillation. Discover the latest research on anti-arrhythmic drug therapies here.

Antiarrhythmic Agents: Mechanisms of Action

Understanding the mechanism of action of antiarrhythmic agents is essential in developing new medications as treatment of cardiac arrhythmias is currently limited by the reduced availability of safe and effective drugs. Discover the latest research on Antiarrhythmic Agents: Mechanism of Action here.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.