PMID: 3745126Sep 1, 1986Paper

Lipid interconversions in aging Mycoplasma capricolum cultures

Journal of Bacteriology
Z Gross, S Rottem

Abstract

During the progression of Mycoplasma capricolum cultures from the early exponential to the stationary phase of growth, a decrease in the phospholipid-to-protein ratio and increases in both the unsaturated-to-saturated fatty acid ratio and the diphosphatidylglycerol (DPG)-to-phosphatidylglycerol (PG) ratio were found. The freedom of motion of spin-labeled fatty acids incorporated into the membrane remained unchanged throughout the growth cycle. The increase in DPG was almost stoichiometric with the decrease in PG. Furthermore, exogenous PG added to the medium was incorporated by the cells and partially converted to DPG. The DPG that was accumulated upon aging was always more unsaturated than the PG. This accumulation was enhanced in palmitic acid-poor media, but was inhibited even in aged cells when the cells were grown in palmitic acid-rich media, suggesting that the accumulation of DPG upon aging was associated with changes in the fatty acid composition of membrane lipids rather than with the transition of the cells from the exponential- to stationary-growth phase.

References

May 1, 1978·FEBS Letters·D RigomierB Lubochinsky
Feb 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·B J Gaffney
Nov 16, 1978·Biochimica Et Biophysica Acta·S Razin
Apr 18, 1977·Biochimica Et Biophysica Acta·A Wieslander, L Rilfors
Mar 24, 1975·Biochimica Et Biophysica Acta·A AudetP Proulx
Jan 1, 1985·Journal of Bacteriology·P J DavisS Rottem
Feb 27, 1973·Biochimica Et Biophysica Acta·S Rottem, A Samuni
Mar 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·C B Hirschberg, E P Kennedy
Feb 14, 1972·Biochimica Et Biophysica Acta·J E Cronan, P R Vagelos
Sep 1, 1967·Biochemistry·P Plackett
Feb 1, 1982·European Journal of Biochemistry·Z GrossR Bittman
Jan 27, 1984·Biochimica Et Biophysica Acta·A J Verkleij
Jun 6, 1980·Biochimica Et Biophysica Acta·S RazinS Rottem
Aug 1, 1959·Canadian Journal of Biochemistry and Physiology·E G BLIGH, W J DYER

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Citations

Aug 1, 2012·Journal of Lipids·Jonathan D Kornspan, Shlomo Rottem
May 9, 2000·Progress in Lipid Research·M SchlameM L Greenberg
Jul 1, 1992·Journal of Bacteriology·M SalmanS Rottem
Jul 1, 1991·Journal of Clinical Microbiology·N S De Silva, P A Quinn

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