Lipid metabolism in uremic and nonuremic acidosis

E Zimmermann, M Hohenegger


In bilaterally nephrectomized rats and in normal rats treated with 0.1 N HCl elevated levels of plasma total glycerol and lowered FFA and free glycerol are observed after a period of 25 h of starvation. In both cases the removal of intravenous lipid loads is slowed down, plasma LA is decreased after starvation and after lipid loads. The bicarbonate treatment of nephrectomized rats tends to normalize the plasma lipid levels and LA as well as the removal of intravenous lipid loads. The etiological importance of acidosis in uremic hypertriglyceridemia and possible clinical significance is pointed out.


Jan 1, 1984·Experimental Pathology·M Hohenegger, H Schuh
Jan 1, 1985·Experimental Pathology·R GottlobM Hohenegger
Jan 1, 1982·Critical Reviews in Clinical Laboratory Sciences·D G Cramp

Related Concepts

Metabolic Acidosis
Carbonic Acid Ions
Nonesterified Fatty Acids
Hydrogen-Ion Concentration
Lipoprotein LIPASE

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