Lipid peroxidation, thiol groups, and total antioxidant capacity in mothers in natural vaginal delivery with and without Entonox: A cohort study

Interventional Medicine & Applied Science
A Ranjbar, Katayon Vakilian

Abstract

Considering that very few studies have been conducted on the effect of Entonox on oxidative stress markers, this study was conducted to compare these markers in natural vaginal delivery (NVD) with and without Entonox. The present cohort study was conducted on 120 women in maternity wards divided into two groups, including an NVD group with and an NVD group without Entonox. After obtaining the mothers' written consent, 5 cc of venous blood was taken at the end of their second stage of labor for lipid peroxidation, thiol groups, and total antioxidant capacity tests. The data obtained were analyzed using descriptive (mean) and inferential (t-test) statistics. Lipid peroxide was 6.267 ± 5.39 in NVD without Entonox and 5.12 ± 3.89 in NVD with Entonox, suggesting the lack of a statistically significant difference (p = 0.191). Thiol marker was 0.34 ± 0.26 in NVD without and 0.26 ± 0.24 in NVD with Entonox, suggesting the lack of a statistically significant difference (p = 0.09).The FRAP results were 0.936 ± 0.696 in NVD without and 1.21 ± 0.89 in NVD with Entonox, suggesting the lack of a statistically significant difference (p = 0.06). Entonox can be safely used in NVD without increasing the risk of oxidative stress.

References

Nov 15, 1978·Clinica Chimica Acta; International Journal of Clinical Chemistry·K Satoh
Dec 16, 2000·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·A NakaiT Araki
Nov 20, 2002·American Journal of Obstetrics and Gynecology·James R WoodsRichard K Miller
Sep 26, 2009·Toxicology Mechanisms and Methods·Katayun VakilianMohammad Abdollahi
Apr 12, 2011·Anesthesiology·Nicholas Riegels, Michael J Richards
Jul 1, 2014·Anesthesiology and Pain Medicine·Nahid Manouchehrian, Mohammad Hossein Bakhshaei

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BETA
cesarean section

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SPSS

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