Lipid peroxidation, vitamins C, E and reduced glutathione levels in patients with pulmonary tuberculosis

Cell Biochemistry and Function
M Vijayamalini, S Manoharan


The present study examined the relationship between lipid peroxidation and vitamin C, vitamin E and reduced glutathione levels in plasma, erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients and an equal number of age-and sex-matched healthy subjects. Enhanced plasma, erythrocytes and erythrocyte membrane lipid peroxidation with concomitant decline in vitamin C, vitamin E and reduced glutathione levels were found in pulmonary tuberculosis patients. The elevated lipid peroxidation and decreased vitamin C, vitamin E and reduced glutathione levels indicate the potential of oxidative damage to erythrocytes and erythrocyte membranes of pulmonary tuberculosis patients.


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Related Concepts

Reduced Glutathione
Tuberculosis, Pulmonary
Vitamin E
Lipid Peroxidation
Thiobarbituric Acid Reactive Substances

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