Lipid, polymeric, inorganic-based drug delivery applications for platinum-based anticancer drugs.

International Journal of Pharmaceutics
Tugce BoztepeIgnacio E León

Abstract

The three main FDA-approved platinum drugs in chemotherapy such as carboplatin, cisplatin, and oxaliplatin are extensively applied in cancer treatments. Although the clinical applications of platinum-based drugs are extremely effective, their toxicity profile restricts their extensive application. Therefore, recent studies focus on developing new platinum drug formulations, expanding the therapeutic aspect. In this sense, recent advances in the development of novel drug delivery carriers will help with the increase of drug stability and biodisponibility, concomitantly with the reduction of drug efflux and undesirable secondary toxic effects of platinum compounds. The present review describes the state of the art of platinum drugs with their biological effects, pre- and clinical studies, and novel drug delivery nanodevices based on lipids, polymers, and inorganic.

References

Oct 1, 1991·Clinical Pharmacokinetics·W J van der Vijgh
Nov 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A H CalvertE Wiltshaw
Apr 26, 1969·Nature·B RosenbergV H Mansour
Jan 1, 1983·European Journal of Cancer & Clinical Oncology·J B VermorkenH M Pinedo
Jan 1, 1982·Cancer Chemotherapy and Pharmacology·A H CalvertK R Harrap
Jan 1, 1995·Journal of Cancer Research and Clinical Oncology·L J van WarmerdamJ H Beijnen
Aug 1, 1994·The International Journal of Biochemistry·A HongoT Kudo
Feb 12, 1998·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M K KuhlmannH Köhler
Aug 24, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R S Go, A A Adjei
Jun 7, 2000·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·J KopecekZ Lu
Aug 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·A de GramontA Bonetti
Mar 27, 2001·Japanese Journal of Cancer Research : Gann·Y MizumuraT Kakizoe
Apr 20, 2001·Advanced Drug Delivery Reviews·W Mehnert, K Mäder
Jun 12, 2001·Annals of Oncology : Official Journal of the European Society for Medical Oncology·K J HarringtonJ S Stewart
Jul 28, 2001·Journal of Biomaterials Applications·R Banerjee
Mar 19, 2002·International Journal of Pharmaceutics·Yvette N KonanEric Allémann
Apr 6, 2002·Cancer Chemotherapy and Pharmacology·Jetske M Meerum TerwogtJan M Schellens
Aug 15, 2002·International Journal of Pharmaceutics·R H MüllerS A Wissing
Mar 4, 2003·Journal of Cellular and Molecular Medicine·Manuela Voinea, Maya Simionescu
Apr 30, 2003·Cancer Chemotherapy and Pharmacology·Joseph T SantosoEdward V Hannigan
Oct 20, 2004·Pediatrics International : Official Journal of the Japan Pediatric Society·Yukie IkarashiMakoto Uchiyama
Dec 14, 2004·Journal of Controlled Release : Official Journal of the Controlled Release Society·Horacio CabralKazunori Kataoka
Dec 21, 2004·Critical Reviews in Oncology/hematology·Stephen G ChaneyYibing Wu
Mar 25, 2005·Nature Reviews. Drug Discovery·Dong Wang, Stephen J Lippard
May 17, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·Rita SongYoun Soo Sohn
Nov 30, 2005·The American Journal of Pathology·Giuliano CiarimboliEberhard Schlatter
Apr 13, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·John R RiceStephen B Howell
Jul 19, 2006·Cancer Chemotherapy and Pharmacology·Tomislav DragovichAxel Hoos
Aug 11, 2006·Nature Reviews. Cancer·Ruth Duncan
Nov 7, 2006·Cancer Treatment Reviews·Cara A Rabik, M Eileen Dolan
Feb 24, 2007·Cancer Metastasis Reviews·Macus Tien KuoToshihisa Ishikawa
Mar 6, 2007·Critical Reviews in Oncology/hematology·David J Stewart
Apr 10, 2007·Critical Reviews in Oncology/hematology·Diane Testart-PailletBrigitte Tranchand
Jul 13, 2007·Nature Reviews. Cancer·Lloyd Kelland
Jul 14, 2007·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sung-Wook Choi, Jung-Hyun Kim
Feb 1, 2008·Journal of Controlled Release : Official Journal of the Controlled Release Society·Jong-Ho KimIck Chan Kwon

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Citations

Oct 29, 2021·Dalton Transactions : an International Journal of Inorganic Chemistry·Liyan WangZhe Liu

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