Abstract
One of the main health problems in many societies is the increased opium abuse, which was found to be correlated with many problems like cardiovascular disease. This study aimed to evaluate the correlation of opium use with blood lipoproteins as the risk factor of CVD. This was a cross-sectional study conducted on participants of the first phase of the PERSIAN Cohort study who were aged between 35 and 70 years old. Demographic characteristics; history of smoking, alcohol, and opium consumption; medical history; and medications were asked and the related checklists were filled out. The levels of physical activity and fat intake were also registered. As well, lipoprotein profiles were investigated by blood sampling. The linear and logistic regression was used to analyze the relationship between opium and lipid profile and the statistical significant level was considered as < 0.05. Among 9300 participants with a mean age of 48.06 ± 9.44 years old, 49.6% of them were men. About 24.1% of the participants used opium. In the linear regression models, unlike TG (β = 2.2, p = 0.36), total cholesterol (β = - 2.5, p = 0.02), LDL (β = - 2.0, p = 0.04), and HDL (β = - 1.0, p = 0.04) were significantly lower in people who used opium compared...Continue Reading
References
May 1, 1987·The Journal of Nutrition·D R RomsosA S Levine
May 12, 2004·The American Journal of Cardiology·Michael MarmorRobert Maslansky
Mar 1, 2006·The Journal of Pharmacology and Experimental Therapeutics·Wei XuLee-Yuan Liu-Chen
Oct 11, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Saeed SadeghianAbbas Ali Karimi
Oct 8, 2008·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·Abbas MohammadiHassan Sheibani
Nov 5, 2008·Lipids in Health and Disease·Sedigheh AsgaryReza Rozbehani
Mar 10, 2010·Sub-cellular Biochemistry·Yamuna Devi Paila, Amitabha Chattopadhyay
May 15, 2010·The American Journal of Drug and Alcohol Abuse·Divsalar KourosMahmoudi Zarandi Minoo
Apr 19, 2012·BMJ : British Medical Journal·Hooman KhademiFarin Kamangar
Jan 16, 2013·International Journal of Cancer. Journal International Du Cancer·Ramin ShakeriFarin Kamangar
Jan 1, 2013·Journal of Addiction·Hasan ZiaaddiniNouzar Nakhaee
Jan 28, 2015·Advanced Biomedical Research·Omid AghadavoudiMohammad Reza Najarzadegan
Jun 23, 2015·International Journal of Preventive Medicine·Hamid NajafipourAli Mirzazadeh
Oct 21, 2016·BMC Public Health·Mojtaba FarjamReza Malekzadeh
Oct 30, 2016·Frontiers in Physiology·Hamid Najafipour, Ahmad Beik
Nov 18, 2017·American Journal of Epidemiology·Hossein PoustchiReza Malekzadeh
Sep 8, 2019·Lancet·Stephanie H Read, Sarah H Wild
Dec 5, 2019·International Journal of Environmental Research and Public Health·Omorogieva OjoJude Ibe
Jan 4, 2020·Substance Abuse Treatment, Prevention, and Policy·Jakob MantheyJürgen Rehm
May 1, 2020·The Lancet Global Health·Mahdi SheikhReza Malekzadeh