Lipid profile of regular kratom (Mitragyna speciosa Korth.) users in the community setting

PloS One
Mohammad Farris Iman Leong Bin AbdullahDarshan Singh

Abstract

Kratom, or Mitragyna speciosa Korth., is a tropical plant that has been reported to exhibit opioid-like effects. Although opioids have been demonstrated to alter the lipid profile of regular users, data on the lipid-altering effects of kratom are scarce. This study aimed to compare the fasting lipid profile of regular kratom users to that of healthy subjects who do not use kratom. It also determined the association between various characteristics of kratom users and the serum triglycerides, total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels of regular kratom users. A total of 200 participants (n = 100 kratom users and n = 100 healthy subjects who do not use kratom) were recruited for this analytical cross-sectional study. Data on sociodemographic status, kratom use characteristics, cigarette smoking, physical activity, body mass index (BMI), fasting serum lipid profile, and liver function were collected from all participants. The liver parameters of the study participants were within normal range. The serum total cholesterol and LDL of kratom users were significantly lower than those of healthy subjects who do not use kratom. There were no significant differences in the serum triglycerid...Continue Reading

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Citations

Dec 18, 2020·Frontiers in Psychiatry·Antonio MetastasioOrnella Corazza
Jul 4, 2021·Drug and Alcohol Dependence·Kirsten E SmithOliver Grundmann
Jul 30, 2021·Frontiers in Pharmacology·Rahimah HassanZurina Hassan
Jul 27, 2021·Human Psychopharmacology·Elisabeth PreveteJohannes Gerardus Ramaekers

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