PMID: 6318073Nov 1, 1983

Lipid radicals--possible mediators of charge transfer and energy transformation (a hypothesis)

Molekuliarnaia biologiia
L F Dmitriev

Abstract

A number of enzymatic reactions with the participation of lipid radicals is discussed in the article. It is supposed that NADPH- and NADH-dependent formation of the lipid radicals has a functional importance. The uptake of oxygen by free radicals is considered as one of the reactions of radicals utilization. It is proposed that other reactions with participation of lipid radicals can take place in the membranes of microsomes and mitochondria: the reaction of electron transfer from flavoprotein to cytochrome P448 and the reaction of energy transfer which provide the coupling of oxidation and phosphorylation.

Related Concepts

Benzo(a)pyrene
Benzpyrene
Respiratory Chain
Energy Metabolism
Free Radicals
Hydroxylation
Lipid Peroxides
NADP
Oxidation-Reduction
Ubiquinone

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