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Lipid remodeling of GPI-anchored proteins and its function

Biochimica Et Biophysica Acta

Oct 5, 2007

Morihisa Fujita, Yoshifumi Jigami

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Abstract

Many proteins are attached to the cell surface via a conserved post-translational modification, the glycosylphosphatidylinositol (GPI) anchor. GPI-anchored proteins are functionally diverse, but one of their most striking features is their association with lipid microdomains, which cons...read more

Mentioned in this Paper

Biochemical Pathway
Post-Translational Protein Processing
Membrane Microdomains
Phosphatidylinositol Glycan
Sphingolipids
Lipids
Protein Targeting
Lipid Metabolism
Anabolism
Saccharomyces cerevisiae
91
Paper Details
References
  • References91
  • Citations64
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  • References91
  • Citations64
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Lipid remodeling of GPI-anchored proteins and its function

Biochimica Et Biophysica Acta

Oct 5, 2007

Morihisa Fujita, Yoshifumi Jigami

PMID: 17913366

DOI: 10.1016/j.bbagen.2007.08.009

Abstract

Many proteins are attached to the cell surface via a conserved post-translational modification, the glycosylphosphatidylinositol (GPI) anchor. GPI-anchored proteins are functionally diverse, but one of their most striking features is their association with lipid microdomains, which cons...read more

Mentioned in this Paper

Biochemical Pathway
Post-Translational Protein Processing
Membrane Microdomains
Phosphatidylinositol Glycan
Sphingolipids
Lipids
Protein Targeting
Lipid Metabolism
Anabolism
Saccharomyces cerevisiae
91

Feeds With Similar Papers

Neurodegeneration: Progranulin & Lipids

Progranulin is a secreted growth factor involved in inflammation, wound healing, cancer, and for its neurotrophic properties. Along with lipids (fats), these molcules are associated with neurodegenerative processes. Here are the latest discoveries pertaining to these molecules and neurodegeneration.

GPI Anchoring

Glycosylphosphatidylinositol (GPI) is a glycolipid anchor for several cell-surface proteins that play a role in various biological processes, including signal transduction, prion disease pathogenesis, and immune response. Here is the latest research.

Related Papers

Paper Details
References
  • References91
  • Citations64
12345...
  • References91
  • Citations64
12345...

Download from

Publisher
PubMed
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