Lipopolysaccharide-dependent enhancement of adherence-mediated chemiluminescence response of polymorphonuclear leukocytes

Journal of Bioluminescence and Chemiluminescence
A DwengerM Funck

Abstract

Adherence of resting polymorphonuclear leukocytes to nylon fibre increased the chemiluminescence response (CL) from 99,400 to 910,300 cpm/25,000 PMNL. This effect could be amplified by lipopolysaccharide (LPS) priming of granulocytes in a dose-dependent fashion. The results of nylon fibre adherence experiments suggest an in vitro model that might approximate certain conditions of in vivo PMNL-endothelial adherence and respiratory burst activation, and these reactions of polymorphonuclear leukocytes may contribute to the pathomechanisms of the Adult Respiratory Distress Syndrome.

References

Mar 1, 1978·The Journal of Clinical Investigation·R R MacGregorN A Kefalides
Sep 26, 1974·The New England Journal of Medicine·R R MacGregorA L Lentnek
Sep 1, 1983·The American Review of Respiratory Disease·R M Tate, J E Repine

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Citations

Mar 1, 1996·European Journal of Clinical Chemistry and Clinical Biochemistry : Journal of the Forum of European Clinical Chemistry Societies·A DwengerG Regel
Mar 1, 1996·Journal of Learning Disabilities·L C Brinckerhoff
May 1, 1993·Journal of Bioluminescence and Chemiluminescence·P De SoleC Guerriero

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