PMID: 8942833Dec 1, 1996Paper

Lipoprotein(a) and other lipids after oophorectomy and estrogen replacement therapy

Obstetrics and Gynecology
F BruschiP G Crosignani

Abstract

To assess the effect of surgical menopause and subsequent estrogen replacement therapy (ERT) on lipoprotein(a) [Lp(a)] and common lipids. In 24 healthy premenopausal women, lipids (total cholesterol, low-density lipoprotein [LDL] and high-density lipoprotein [HDL] cholesterol, and triglycerides) and gonadotropins (FSH, LH) were measured the day before hysterectomy with bilateral oophorectomy and then after 1, 2, and 3 months. Blood was also drawn after 2, 4, 6, and 15 days to exclude the effect of surgery on Lp(a). In 19 women who volunteered for ERT, the lipid profile was assayed again after 3, 6, and 12 months of treatment. Lipoprotein(a) levels rose significantly over the 3 months after surgery, from a mean +/- standard deviation (SD) 5.7 +/- 6.1 mg/dL to 10.4 +/- 9.2 mg/dL. Total cholesterol and LDL cholesterol levels increased significantly over the first 2 months; HDL cholesterol decreased significantly during the 3 months of follow-up (by 10, 17, and 20%) (P < .001). Plasma triglycerides did not change after surgery. Three months following ERT, Lp(a) and total cholesterol were significantly decreased (28 and 11%, respectively), as was LDL cholesterol (33%) after 6 months. High-density lipoprotein cholesterol increased by...Continue Reading

References

Dec 1, 1978·Lipids·J J AlbersM C Chenng
Jul 1, 1992·The Journal of Clinical Investigation·E BoerwinkleH H Hobbs
Jan 1, 1992·Atherosclerosis·D CrookJ C Stevenson
Sep 21, 1991·BMJ : British Medical Journal·E FarishD M Hart
Sep 4, 1990·The American Journal of Cardiology·P W Wilson
Jan 1, 1990·British Journal of Obstetrics and Gynaecology·E FarishM L Smith
Aug 1, 1989·Atherosclerosis·S MaedaM Kawade
Oct 1, 1989·British Journal of Obstetrics and Gynaecology·J C MontgomeryJ W Studd
Jan 1, 1984·Gynecologic and Obstetric Investigation·F PansiniG Mollica
Sep 1, 1993·Acta Endocrinologica·E FarishD M Hart
Feb 1, 1994·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·C J KimY K Min

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Citations

Jul 31, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·O Gökmen, E G Yapar Eyi
Nov 13, 2004·The Journal of Nutritional Biochemistry·E SohnB H Arjmandi
Jun 29, 2006·Journal of Nutritional Science and Vitaminology·Xiong LiuKiyoshi Ebihara
Sep 19, 2007·Journal of Nutritional Science and Vitaminology·Junichi MatsumotoKiyoshi Ebihara
Apr 20, 2014·Metabolism: Clinical and Experimental·Wasana PratchayasakulSiriporn C Chattipakorn
Nov 1, 2006·Women's Health·Giuseppe Mc RosanoGiuseppe Mercuro
Mar 9, 2013·Molecular Nutrition & Food Research·Lei ZhangXiong Liu
Oct 28, 2004·American Journal of Obstetrics and Gynecology·Sean C DowdyLynn C Hartmann
Dec 30, 2016·International Journal of Clinical Practice·Panagiotis AnagnostisDimitrios G Goulis
May 27, 1999·The Proceedings of the Nutrition Society·A Cassidy, B Griffin
Nov 25, 2003·Menopause : the Journal of the North American Menopause Society·Majoie HemelaarPeter Kenemans
Nov 14, 1998·Annals of Medicine·M R Taskinen
Apr 11, 2013·Menopause : the Journal of the North American Menopause Society·Sara C CampbellBahram H Arjmandi
Jul 10, 1999·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·V MijatovicP Kenemans
Jul 10, 1999·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·E M AygenM Başbuğ
Feb 27, 2015·Oncotarget·Valeria BenedusiAdriana Maggi

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