Lipoproteins for therapeutic delivery: recent advances and future opportunities

Therapeutic Delivery
Sangram RautAndras G Lacko

Abstract

The physiological role(s) of mammalian plasma lipoproteins is to transport hydrophobic molecules (primarily cholesterol and triacylglycerols) to their respective destinations. Lipoproteins have also been studied as drug-delivery agents due to their advantageous payload capacity, long residence time in the circulation and biocompatibility. The purpose of this review is to briefly discuss current findings with the focus on each type of formulation's potential for clinical applications. Regarding utilizing lipoprotein type formulation for cancer therapeutics, their potential for tumor-selective delivery is also discussed.

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Citations

Aug 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Karin KornmuellerRuth Prassl
Dec 5, 2019·Biomaterials Science·S BusattoP Bergese
Jan 26, 2020·International Journal of Molecular Sciences·Jiansheng HuangHui Huang
Jan 17, 2020·The Journal of Pharmacology and Experimental Therapeutics·Sangram RautAndras Lacko
Dec 19, 2019·International Journal of Molecular Sciences·Jaideep ChaudharyIan R Corbin
Jun 11, 2019·Frontiers in Bioengineering and Biotechnology·Milad Fathi-AchacheloueiNihal Engin Vrana
Nov 7, 2018·Current Atherosclerosis Reports·Maki TsujitaAlan T Remaley
Apr 17, 2020·Frontiers in Cardiovascular Medicine·Anne Jomard, Elena Osto
Jan 25, 2021·International Journal of Pharmaceutics·Aditya GuptaSanyog Jain
Jun 21, 2020·Chemistry and Physics of Lipids·Liliana Aranda-LaraKeila Isaac-Olivé
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Jul 21, 2020·Trends in Endocrinology and Metabolism : TEM·Reinaldo Barreto OriáJosé Ricardo Figueiredo
Nov 15, 2020·Seminars in Cancer Biology·Samuel C DelkSrinivasa T Reddy
Jul 29, 2021·ACS Applied Materials & Interfaces·Hyunseok OhDae-Hyuk Kweon

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Software Mentioned

CARAT
PILOT

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