Liposome encapsulation of curcumin: physico-chemical characterizations and effects on MCF7 cancer cell proliferation

International Journal of Pharmaceutics
Mahmoud HasanElmira Arab-Tehrany

Abstract

The role of curcumin (diferuloylmethane), for cancer treatment has been an area of growing interest. However, due to its low absorption, the poor bioavailability of curcumin limits its clinical use. In this study, we reported an approach of encapsulation a curcumin by nanoliposome to achieve an improved bioavailability of a poorly absorbed hydrophobic compound. We demonstrated that liposomal preparations to deliver curcumin increase its bioavailability. Liposomes composed of salmon's lecithin also improved curcumin bioavailability compared to those constituted of rapeseed and soya lecithins. A real-time label-free cell analysis system based on real-time cell impedance monitoring was used to investigate the in vitro cytotoxicity of liposomal preparations.

References

Aug 1, 1976·Biochemical Pharmacology·O P Sharma
Jan 1, 1984·Progress in Biophysics and Molecular Biology·J C EdwardsM B Yatvin
Jan 1, 1993·Molecular Aspects of Medicine·K H Cheeseman
Aug 1, 1997·Journal of Pharmaceutical and Biomedical Analysis·Y J WangJ K Lin
Apr 3, 1999·Journal of Pharmaceutical Sciences·G ChansiriS L Hem
Jul 8, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·L CoderchJ L Parra
Mar 22, 2002·The Lancet Oncology·A J GescherW P Steward
May 15, 2002·Radiation Research·Dipti Marathe, K P Mishra
Sep 3, 2002·International Journal of Pharmaceutics·Hanne Hjorth TønnesenThorsteinn Loftsson
Jul 16, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Miechel L T ZweersJan Feijen
Oct 20, 2005·Journal of Biomolecular Screening·Josephine M AtienzaYama Abassi
Dec 27, 2005·Cell Biology International·Mingxin ShiGaoliang Ouyang
Jul 6, 2006·Journal of the American Chemical Society·Praveen Kumar VemulaGeorge John
Nov 23, 2006·International Journal of Pharmaceutics·Kuntal MaitiPulok K Mukherjee
Nov 23, 2006·Assay and Drug Development Technologies·Shelli L KirsteinYama A Abassi
Feb 9, 2007·International Journal of Pharmaceutics·Waree TiyaboonchaiPinyupa Plianbangchang
Apr 19, 2007·Journal of Nanobiotechnology·Savita BishtAnirban Maitra
Jun 2, 2007·Journal of Agricultural and Food Chemistry·John A BenedetTakayuki Shibamoto
Nov 15, 2007·Molecular Pharmaceutics·Preetha AnandBharat B Aggarwal
Dec 8, 2007·International Journal of Pharmaceutics·Keitaro SouEishun Tsuchida
Jan 8, 2008·Biochimica Et Biophysica Acta·A KunwarK I Priyadarsini
Mar 1, 2008·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Feng-Lin YenChun-Ching Lin
Jun 24, 2008·Chemico-biological Interactions·Arnab BanerjeeK I Priyadarsini
Mar 28, 2009·International Journal of Cancer. Journal International Du Cancer·Narayanan K NarayananBhagavathi A Narayanan
May 30, 2009·Nature Reviews. Drug Discovery·Dunyaporn TrachoothamPeng Huang
Nov 27, 2009·Postgraduate Medicine·Philip C Calder, Parveen Yaqoob
Jul 16, 2010·Journal of Colloid and Interface Science·Murali Mohan YallapuSubhash C Chauhan
May 4, 2011·International Journal of Biological Macromolecules·N Sanoj RejinoldR Jayakumar
May 31, 2011·Biotechnology Advances·Feroz AkhtarSantosh Kumar Kar
Dec 14, 2011·The Analyst·Behnoush MaheraniMichel Linder
Jan 31, 2012·Journal of Colloid and Interface Science·Letícia MazzarinoRedouane Borsali
Apr 10, 2012·Colloids and Surfaces. B, Biointerfaces·Elmira Arab TehranyMichel Linder

❮ Previous
Next ❯

Citations

Dec 17, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marie-Hélène TeitenMarc Diederich
Nov 23, 2015·Colloids and Surfaces. B, Biointerfaces·Marco PainiPeter Valtchev
Apr 22, 2016·Bioscience, Biotechnology, and Biochemistry·Haisong ZhangXinwu Ba
Apr 27, 2016·Journal of Controlled Release : Official Journal of the Controlled Release Society·Askell Hvid HinnaMartin Brandl
Nov 8, 2016·Journal of Drug Targeting·Anup JoseVenkata Vamsi Krishna Venuganti
Feb 25, 2015·Food & Function·Maria Inês DiasMaria Filomena Barreiro
Jun 9, 2018·Critical Reviews in Food Science and Nutrition·Elham Assadpour, Seid Mahdi Jafari
Oct 21, 2017·Journal of Food Science and Technology·Mahia RoostaeeZahra Rafiee
Jan 10, 2019·Cancer Biology & Therapy·Xiuming ZhangWenrong Shen
Feb 7, 2019·Journal of Gastrointestinal Cancer·Tohid HassanalilouLeila Khalili
May 17, 2019·Journal of Microencapsulation·Mangat SinghVivek Ahluwalia
Jun 18, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Xia XueRong-Mei Wang
Apr 3, 2020·Journal of Cellular Physiology·Mohammad PanahiEffat Alizadeh
Jul 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Asmaa MechetaMichel Linder
Aug 14, 2019·Advanced Healthcare Materials·Kamil ElkhouryAli Tamayol
May 21, 2017·Nanoscale Research Letters·Andri HardiansyahTzu-Yi Chan
Feb 7, 2018·Luminescence : the Journal of Biological and Chemical Luminescence·Qingyun GaoChangying Yang
Jul 22, 2019·Marine Drugs·Catherine MalaplateFrances T Yen
Jul 17, 2020·Environmental Science and Pollution Research International·Mahsan BeyramiEhsan Oskoueian
Jun 9, 2020·Frontiers in Immunology·Edward B ThorpXunrong Luo
Jan 28, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yan LiShicheng Wei
Feb 23, 2020·Frontiers in Pharmacology·Xiaowen CaiChuanshan Xu
May 18, 2020·International Journal of Molecular Sciences·Arnaud BianchiElmira Arab-Tehrany
Dec 14, 2017·International Journal of Molecular Sciences·Kamel RahaliElmira Arab-Tehrany
Mar 11, 2020·Biological Trace Element Research·Negin ShafaeiEhsan Oskoueian
Apr 16, 2020·Journal of Liposome Research·Mahshid Moballegh-NaseryMohadeseh Mohammadi
May 30, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mahmoud HasanMichel Linder
Oct 7, 2020·International Journal of Molecular Sciences·Elmira Arab-TehranyMichel Linder
Dec 3, 2020·International Journal of Molecular Sciences·Daria V KuznetcovaFrances T Yen
Feb 13, 2021·International Journal of Biological Macromolecules·Pier Francesco FerrariDomenico Palombo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.