Liposomes and their applications in molecular imaging

Journal of Drug Targeting
Mine SilindirSerge Maia

Abstract

Molecular imaging is a relatively new discipline with a crucial role in diagnosis and treatment tracing of diseases through characterization and quantification of biological processes at cellular and sub-cellular levels of living organisms. These molecular targeted systems can be conjugated with contrast agents or radioligands to obtain specific molecular probes for the purpose of diagnosis of diseases more accurately by different imaging modalities. Nowadays, an interesting new approach to molecular imaging is the use of stealth nanosized drug delivery systems such as liposomes having convenient properties such as biodegradability, biocompatibility and non-toxicity and they can specifically be targeted to desired disease tissues by combining with specific targeting ligands and probes. The targeted liposomes as molecular probes in molecular imaging have been evaluated in this review. Therefore, the essential point is detection of molecular target of the disease which is different from normal conditions such as increase or decrease of a receptor, transporter, hormone, enzyme etc, or formation of a novel target. Transport of the diagnostic probe specifically to targeted cellular, sub-cellular or even to molecular entities can be ...Continue Reading

References

Jul 1, 1992·International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology·W T PhillipsR Blumhardt
Apr 1, 1989·Radiology·S E Seltzer
Mar 1, 1988·Radiology·A F TurnerJ L Werner
Aug 1, 1965·Journal of Molecular Biology·A D BanghamJ C Watkins
Jul 1, 1995·Pharmaceutica acta Helvetiae·S Vemuri, C T Rhodes
Mar 15, 1994·Proceedings of the National Academy of Sciences of the United States of America·R H BoboE H Oldfield
Feb 1, 1993·European Journal of Nuclear Medicine·A KuboT Teramoto
May 1, 1996·Journal of Pharmaceutical Sciences·H Alkan-OnyukselD D McPherson
May 1, 1996·Journal of Microencapsulation·J Al-MuhammedA A Hincal
Sep 1, 1996·Journal of Microencapsulation·F S FarshiA A Hincal
Feb 14, 1998·Nature Medicine·P R ContagC H Contag
Mar 18, 1999·Journal of the American College of Cardiology·S M DemosD D McPherson
Sep 3, 1999·Nuclear Medicine and Biology·S S GambhirM E Phelps
Mar 4, 2000·Journal of Controlled Release : Official Journal of the Controlled Release Society·H MaedaK Hori
Jul 18, 2000·Journal of Microencapsulation·S ErdoganA A Hincal
Nov 1, 2000·Echocardiography·D RovaiA L'Abbate
Apr 27, 2001·Radiology·R Weissleder, U Mahmood
Jul 27, 2001·Current Pharmaceutical Biotechnology·V P Torchilin
Sep 5, 2001·Progress in Cardiovascular Diseases·G M Lanza, S A Wickline
Feb 19, 2002·Current Opinion in Biotechnology·Warren C W ChanShuming Nie
Mar 14, 2002·Biochemical and Biophysical Research Communications·Jianwei J LiWeihong Tan
Jul 23, 2002·Nature Biotechnology·J Manuel PerezRalph Weissleder
Nov 14, 2002·Bioscience Reports·Yong Serk Park
Mar 12, 2003·Genes & Development·Tarik F Massoud, Sanjiv S Gambhir
Jun 20, 2003·Progress in Lipid Research·P Sapra, T M Allen
Aug 23, 2003·Journal of Controlled Release : Official Journal of the Controlled Release Society·Sumeet DagarHayat Onyüksel
Aug 27, 2003·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Viktor SzatmáriKároly Vörös
Jan 13, 2004·Methods in Enzymology·Peter LavermanGert Storm
Apr 28, 2004·Advanced Drug Delivery Reviews·Anatoly N Lukyanov, Vladimir P Torchilin
May 26, 2004·Cardiology Clinics·Flordeliza S VillanuevaJagat Narula
Oct 19, 2004·Neuropathology and Applied Neurobiology·E A NeuweltR Nixon
Feb 18, 2005·NeuroRx : the Journal of the American Society for Experimental NeuroTherapeutics·Anita Schnyder, Jörg Huwyler
Mar 16, 2005·Biochemical and Biophysical Research Communications·Harinder AryaSunil C Kaul
Apr 26, 2005·International Journal of Pharmaceutics·Suna ErdoğanHasan Bilgili
May 12, 2005·International Journal of Pharmaceutics·Selcan TürkerSalih Deveci
Sep 10, 2005·Nature Biotechnology·Gregory P Adams, Louis M Weiner
Mar 25, 2006·Journal of Liposome Research·Suna ErdoganVladimir P Torchilin

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Citations

Sep 13, 2012·Investigative Ophthalmology & Visual Science·Walid F AbdallahMark S Humayun
Oct 20, 2012·Journal of Liposome Research·Mine SilindirVladimir P Torchilin
Nov 26, 2015·Accounts of Chemical Research·Kim Truc Nguyen, Yanli Zhao
Dec 18, 2013·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Gregory M LanzaKeyvan Farahani
May 27, 2015·Chemical Reviews·Bhushan S PattniVladimir P Torchilin
Nov 5, 2016·Colloids and Surfaces. B, Biointerfaces·Gaoxin ZhouMin Ji
Mar 21, 2019·Drug Development Research·Mine Silindir-GunayAsuman Yekta Ozer
Apr 18, 2020·Cancer Biotherapy & Radiopharmaceuticals·Mine Silindir-GunayA Yekta Ozer
Apr 11, 2018·Cancer Biotherapy & Radiopharmaceuticals·Merve KarpuzAsuman Yekta Ozer
Oct 15, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jabadurai Jayapaul, Leif Schröder
Feb 2, 2018·The Journal of Physical Chemistry Letters·Bong Jin HongSonBinh T Nguyen

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