PMID: 2508785Jul 1, 1989Paper

Lipoxin B, an enhancing factor of spontaneous platelet aggregation in whole blood

Biulleten' eksperimental'noĭ biologii i meditsiny
A L KhshivoG K Popov

Abstract

The arachidonic acid metabolites, lipoxin B (5,14,15-trihydroxy-6,8,10,12-eicosatetraenoate) and 5,15-dihydroxy-eicosatetraenoate were shown to possess a marked effect on platelet aggregation and procoagulant activity. Lipoxin B increases and 5,15-dihydroxy-eicosatetraenoate decreases spontaneous platelet aggregation and procoagulant activity when added at various concentrations. The drugs tested were found to have no direct action on blood coagulation.

References

Feb 1, 1986·Prostaglandins, Leukotrienes, and Medicine·M R BuchananD J Nazir
Jul 1, 1986·Prostaglandins·M LecomteJ M Boeynaems
Nov 24, 1986·FEBS Letters·H KühnH Stender
Apr 25, 1985·Biochimica Et Biophysica Acta·P HenrikssonU Diczfalusy
Aug 1, 1971·Biulleten' eksperimental'noĭ biologii i meditsiny·V P BaludaS S Khnychev

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Citations

Jul 20, 2005·Bulletin of Experimental Biology and Medicine·V I Yan'kova, T A Gvozdenko

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