PMID: 16528915Mar 15, 2006Paper

Liquid Tissue: proteomic profiling of formalin-fixed tissues

BioTechniques
DaRue A PrietoDavid B Krizman

Abstract

Identification and quantitation of candidate biomarker proteins in large numbers of individual tissues is required to validate specific proteins, or panels of proteins, for clinical use as diagnostic, prognostic, toxicological, or therapeutic markers. Mass spectrometry (MS) provides an exciting analytical methodology for this purpose. Liquid Tissue MS protein preparation allows researchers to utilize the vast, already existing, collections offormalin-fixed paraffin-embedded (FFPE) tissues for the procurement of peptides and the analysis across a variety of MS platforms.

References

Apr 29, 1998·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·K IkedaM Monden
Jul 18, 2001·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S R ShiC R Taylor
Feb 13, 2002·The American Journal of Pathology·John W GillespieMichael R Emmert-Buck
Feb 28, 2002·Lancet·Emanuel F PetricoinLance A Liotta
Apr 11, 2003·Proteomics·Mamoun AhramMichael R Emmert-Buck
Jun 5, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Tatyana A ZhukovMelvyn S Tockman
Feb 12, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jens KoopmannMichael Goggins
Apr 29, 2004·Journal of Proteome Research·Pierre ChaurandRichard M Caprioli

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Citations

May 29, 2007·Laboratory Investigation; a Journal of Technical Methods and Pathology·Carol B FowlerJeffrey T Mason
Feb 23, 2011·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Shan-Rong ShiClive R Taylor
Nov 15, 2011·The Journal of Pathology·Kalnisha NaidooTatjana Crnogorac-Jurcevic
Feb 3, 2011·Journal of Clinical Pathology·Lynda D Ralton, Graeme I Murray
Jun 29, 2011·Expert Review of Anticancer Therapy·Renato FrancoGerardo Botti
Jan 4, 2012·Proteomics. Clinical Applications·Alessandro TancaMaria Filippa Addis
Apr 12, 2013·Expert Review of Proteomics·Laura Giusti, Antonio Lucacchini
Dec 14, 2016·Annual Review of Pathology·Ahmet Dogan
Sep 19, 2019·Laboratory Investigation; a Journal of Technical Methods and Pathology·Kouhei YamamotoMasanobu Kitagawa
Sep 16, 2006·Electrophoresis·Tong GuoBrian M Balgley
Apr 5, 2007·Nature Protocols·Virginia EspinaLance A Liotta
May 28, 2009·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Marshall S ScicchitanoKendall S Frazier
May 23, 2012·Analytical and Bioanalytical Chemistry·Cordula KlockenbuschJuergen Kast
Sep 3, 2013·Expert Review of Proteomics·Carol B FowlerJeffrey T Mason
Apr 19, 2015·Breast Cancer Research : BCR·Paolo NuciforoMaurizio Scaltriti
Jan 17, 2017·Laboratory Investigation; a Journal of Technical Methods and Pathology·Maria I TokiDavid L Rimm
May 17, 2019·Expert Review of Proteomics·Laura GiustiAntonio Lucacchini
Aug 30, 2005·Laboratory Investigation; a Journal of Technical Methods and Pathology·Wei-Sing ChuMaokai Gong
Jul 20, 2007·Proteomics·Ferdinand von EggelingGünther Ernst
Jan 10, 2006·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Shan-Rong ShiClive R Taylor
Sep 1, 2009·Proteomics·Maria Filippa AddisSergio Uzzau
Oct 1, 2008·Proteomics. Clinical Applications·Joon-Yong ChungStephen M Hewitt
Apr 10, 2010·Expert Review of Proteomics·Kant M MatsudaStephen M Hewitt
Aug 24, 2012·International Journal of Cancer. Journal International Du Cancer·Tatsuyuki TakadateMichiaki Unno
Jul 30, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Tetsushi YamamotoZenya Naito
Jun 6, 2008·Expert Review of Proteomics·Karim RezaulDavid K Han
Aug 12, 2014·Omics : a Journal of Integrative Biology·Rémi LonguespéeEdwin De Pauw
Mar 9, 2017·Expert Review of Proteomics·Kiyonaga FujiiToshihide Nishimura
Apr 29, 2015·Journal of Hepato-biliary-pancreatic Sciences·Shimpei MaedaMichiaki Unno
Sep 26, 2007·Expert Review of Molecular Diagnostics·Virginia EspinaLance A Liotta

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