Listeria grayi: vancomycin-resistant, gram-positive rod causing bacteremia in a stem cell transplant recipient

Transplant Infectious Disease : an Official Journal of the Transplantation Society
H SalimniaP H Chandrasekar

Abstract

We report the first case of Listeria grayi bacteremia in a stem cell transplant recipient. The patient developed bacteremia with a gram-positive rod that was initially thought to be Corynebacterium species and a skin contaminant. The organism grew in multiple blood cultures and therapy with vancomycin was initiated. The API Coryne (version 3.0) identified the organism as L. grayi. Susceptibility testing by Etest suggested that the organism was resistant to vancomycin, but susceptible to ampicillin. After therapeutic change from vancomycin to ampicillin, the bacteremia cleared. Empiric therapy with vancomycin for all gram-positive bacterial infections is not appropriate. Accurate identification and antibiotic susceptibility is important, particularly in those with persistent bacteremia.

References

Jan 29, 1999·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·G TodeschiniR Corrocher
Oct 17, 2006·Clinical Microbiology Reviews·Keri K Hall, Jason A Lyman
Sep 25, 2008·Transplant Infectious Disease : an Official Journal of the Transplantation Society·A RaposeN Ismail

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Citations

Nov 11, 2011·International Journal of Molecular Sciences·Dambudzo Penduka, Anthony I Okoh
Jul 25, 2014·Annals of Clinical Microbiology and Antimicrobials·Dambudzo PendukaAndy Opoku
Sep 25, 2021·Scientific Reports·Stephen EricksonMinh M Nguyen

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