Lithium and male sexual function in affective patients

Clinical Neuropharmacology
D AizenbergAbraham Weizman

Abstract

The aim of the present study was to evaluate sexual function and behaviour in male patients who take lithium. Participants included 35 bipolar and schizoaffective men, aged 43.3 +/- 9.6 years, who were in euthymic state and were receiving lithium as the sole medical treatment. Eleven patients (31.4%) reported sexual dysfunction on at least two items of the sexual function questionnaire. Notable results were reduction in frequency of sexual thoughts and loss of erection during sex in 23 and 20% of patients, respectively. Difficulties in achieving and maintaining erections (ease of arousal) were reported in 14% of patients. Nevertheless, almost all patients reported preserved pleasure during sexual activity and were satisfied with their sexual performance. There was no difference in serum lithium levels in patients with and without sexual dysfunction. No statistical correlation was found between sexual function scores and serum lithium levels. Lithium therapy may impair desire and arousal, yet it does not appear to have a major impact on patient self-satisfaction or subjective sense of pleasure during sexual activity. The degree of sexual dysfunction as reported in the present study was not a source of distress to patients and di...Continue Reading

Citations

Nov 14, 2003·Reproductive Toxicology·Sonu Chand ThakurShiv P Singh
Jan 6, 2010·Indian Journal of Psychiatry·Anil Kumar M NagarajSatheesh Rao
Apr 16, 2011·Trends in Pharmacological Sciences·Mehdi Ghasemi, Ahmad Reza Dehpour
Jul 8, 2010·The Journal of Surgical Research·Behtash Ghazi NezamiAhmad Reza Dehpour
Jan 27, 2015·Human Psychopharmacology·Hesham Y ElnazerDavid Baldwin
Jul 11, 2006·Nitric Oxide : Biology and Chemistry·Hamed SadeghipourAhmad Reza Dehpour
Nov 10, 2015·The Journal of Sexual Aggression·Amy D LykinsJames M Cantor
Aug 16, 2016·The Psychiatric Clinics of North America·Anita H ClaytonJennifer G Votta
Nov 26, 2013·International Journal of Law and Psychiatry·Rigmor R Diseth, Per A Høglend
Aug 15, 2000·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·E Perez RomeraJ A Guzmán
Nov 24, 2006·International Journal of Andrology·O Zarnescu, G Zamfirescu
Jul 30, 2010·Clinical Pharmacology and Therapeutics·A Serretti, A Chiesa
Jun 11, 2009·Journal of Clinical Psychopharmacology·Sidney H Kennedy, Sakina Rizvi
Jun 28, 2002·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Robert Taylor Segraves
May 2, 2014·Journal of Clinical Psychopharmacology·Sandeep GroverAjit Avasthi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.