Lithium interferes with reserpine-induced dopamine depletion

Annals of Neurology
A RechesS Fahn

Abstract

Long-term lithium treatment attenuated the hypokinetic effect of reserpine in a patient with tardive dyskinesia. In rats, prophylactic lithium administration inhibits reserpine-induced dopamine depletion in the brain. These data indicate that lithium may limit the therapeutic efficacy of reserpine in tardive dyskinesia.

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Citations

Aug 29, 2000·Journal of the Neurological Sciences·U B MuthaneP Satishchandra
Apr 1, 1995·Journal of Geriatric Psychiatry and Neurology·S Holroyd, D Smith
Feb 1, 1984·Annals of Neurology·A E Lang

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