Lithium ratio in vitro: familial patterns of illness

Psychiatry Research
F SautterD L Garver

Abstract

Psychiatric illness in first-degree relatives of psychotic patients with low, intermediate, and high red blood cell (RBC) in vitro lithium ratio (LR) was investigated using the Schedule for Affective Disorders and Schizophrenia and DSM-III. Fewer schizophrenic spectrum disorders were found in the first-degree relatives of high and low LR probands as compared to intermediate LR probands; high LR psychotic probands had families with an increased frequency of depressive spectrum disorder. Alcohol dependence and abuse was particularly prominent in the first-degree relatives of the higher LR probands. High LR may identify a disease that does not belong to the familial-genetic disorders of the schizophrenic spectrum; this illness may bear a closer relationship to disorders of the depressive spectrum.

References

Aug 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·G N PandeyD C Tosteson
Aug 1, 1978·The Journal of General Physiology·G N PandeyD C Tosteson
Nov 1, 1978·The Journal of Nervous and Mental Disease·G WinokurM Lowry
Feb 1, 1976·The American Journal of Psychiatry·S W Matthysse, K K Kidd
Apr 1, 1985·Archives of General Psychiatry·K R MerikangasM M Weissman
Jan 1, 1985·Journal of Psychiatric Research·F Sautter, D Garver
Jan 1, 1973·The Journal of Nervous and Mental Disease·I Marks, M Lader
Aug 1, 1966·The British Journal of Psychiatry : the Journal of Mental Science·L L Heston
May 1, 1984·Psychiatry Research·D L GarverP E Djuric
Sep 1, 1983·Archives of General Psychiatry·A L von KnorringS Sigvardsson
Nov 1, 1983·The American Journal of Psychiatry·M BaronJ Kane
Jul 1, 1982·Archives of General Psychiatry·A W LorangerE H Tulis
Aug 1, 1980·The American Journal of Psychiatry·J HirschowitzS Chang

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Citations

May 17, 1990·Klinische Wochenschrift·M Ruiz MartínezV Moreno-Abadía

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