Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment

PloS One
Joyce ChaiErnest Hung-Yu Ng

Abstract

To determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders. Retrospective analysis. University infertility clinic. A total of 1,152 subfertile women undergoing their first in vitro fertilization (IVF) cycle. Women were classified into 4 groups according to the Bologna criteria for comparison. Live birth and cumulative live birth rates. Women with expected poor response (POR) had the lowest live birth rate than the other 3 groups (23.8%, p = 0.031). Cumulative live birth rates were significantly lower in those with expected POR than those with expected normal ovarian response (NOR) (35.8% vs 62.8%, p<0.0001). In the subgroup analysis, the cumulative live birth rates in expected PORs were significantly lower in those who had ≤3 oocytes retrieved (18.6% for ≤3 oocytes vs 44.0% for >3 oocytes, p = 0.006) whereas the live birth rates in fresh cycle did not differ (17.8% vs 30.9%, p = 0.108). Women who were expected POR according to the Bologna criteria had lower live birth and cumulative live birth than expected NOR but they still can achieve reasonable treatment outcomes and IVF treatment sho...Continue Reading

References

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Citations

Nov 19, 2015·Journal of Ovarian Research·Johnny S YounisIzhar Ben-Shlomo
Mar 4, 2017·Gynécologie, Obstétrique, Fertilité & Sénologie·C Sifer
Apr 20, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Rui HuangXiao-Yan Liang
May 30, 2019·Frontiers in Endocrinology·Valentina GrisendiAntonio La Marca
May 20, 2020·Journal of Gynecology Obstetrics and Human Reproduction·Banu SevenYaprak Engin-Ustun
May 28, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Mehri MashayekhiZahra Zolfaghari

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Methods Mentioned

BETA
hormone replacement
ELISA

Software Mentioned

Statistical Program for Social Sciences ( SPSS

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