Livedoid vasculopathy: Clinical course and long-term outcome in Asian patients with a review of the literature.

Dermatologic Therapy
Chuda RujitharanawongSasipha Nuttawong

Abstract

Livedoid vasculopathy (LV) is an uncommon, chronic, and recurrent thrombo-occlusive vascular disorder. Data specific to LV in Thai population remains scarce. This study aimed to evaluate the clinical course and treatment outcomes of LV in Thai patients, and to perform a literature review for studies that reported on anticoagulant treatment in LV. Seventy-four patients with a mean age of 37.6 ± 14.7 years were included. The female to male ratio was 5.2:1, and the median follow-up was 10.5 months. Most patients had primary LV disorder. Forty-eight patients were improved with treatments, with a median duration of 11.4 months. Combination treatments were commonly used, including anti-inflammatories, antiplatelets, and immunosuppressants. Add-on therapy with anticoagulant or psoralen plus ultraviolet-A (PUVA) led to disease improvement in a majority of the patients treated. Kaplan-Meier analysis demonstrated that 38.5%, 53.7%, and 57.9% would have disease improvement at 1, 2, and 3 years, respectively. Of 39 studies (n = 219) that reported on anticoagulant treatment in LV, anticoagulant drug was used as monotherapy in 104 patients. The mean duration of anticoagulant treatment was 7.2 ± 3.8 months, which led to disease improvement in...Continue Reading

References

Jan 1, 1983·Journal of the American Academy of Dermatology·R L Jetton, G S Lazarus
Aug 20, 2003·Archives of Dermatology·Bethany R HairstonLisa A Drage
Aug 18, 2004·Archives of Dermatology·Camille Francès, Stéphane Barete
May 13, 2005·Photodermatology, Photoimmunology & Photomedicine·C TuchindaH W Lim
Jan 18, 2006·Archives of Dermatology·Catherine E Browning, Jeffrey P Callen
Feb 19, 2008·Journal of the American Academy of Dermatology·Mark D P Davis, Waldemar E Wysokinski
May 20, 2008·The Journal of Dermatological Treatment·Mukaddes KavalaSumeyye Altintas
Feb 24, 2010·The Journal of Dermatology·Shin-Ichi OsadaSeiji Kawana
Mar 27, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·T B Di GiacomoP R Criado
Dec 28, 2010·Autoimmunity Reviews·Paulo Ricardo CriadoJozélio Freire de Carvalho
Jan 12, 2011·The British Journal of Dermatology·R VasconcelosW Belda
Sep 15, 2011·European Journal of Dermatology : EJD·Satoshi NakamuraHajime Iizuka
Oct 31, 2012·The British Journal of Dermatology·N KerkT Goerge
Sep 14, 2013·Journal of the American Academy of Dermatology·Afsaneh AlaviRobert S Kirsner
Dec 20, 2013·Acta Dermato-venereologica·Suiying FengChanggeng Shao
Sep 27, 2014·The British Journal of Dermatology·D S WinchesterM D P Davis
Jun 1, 2011·Einstein·Patricia Weinschenker BollmannAuro Del Giglio
Mar 20, 2016·Clinical and Experimental Dermatology·J M Lee, I-H Kim
Apr 7, 2016·JAAD Case Reports·John M EvansNaveed Sami
May 12, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·Y YamaguchiH Shimizu
Jan 5, 2017·Clinical and Experimental Dermatology·T Sawada, M Suehiro
Apr 1, 2017·Journal of Pain Research·Wenji ChenXiaohu Deng
Jun 14, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·C Drerup, T Goerge
Nov 16, 2017·JAMA Dermatology·Robert Micieli, Afsaneh Alavi
Apr 18, 2018·International Journal of Dermatology·Gabriela Franco MarquesMaría Salomé Cajas García
May 9, 2018·Acta Dermato-venereologica·Emma GardetteStéphane Barete
Aug 14, 2018·Autopsy & Case Reports·Thiago Quadrante FreitasPaulo Ricardo Criado
Aug 30, 2018·The Journal of Dermatology·Shin-Ichi OsadaMotomu Manabe
Feb 16, 2019·Clinical and Experimental Dermatology·D MiguelS Goetze
Apr 23, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·C WeishauptT Goerge
Dec 4, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·J S Lee, S Cho

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