Liver assessment using Gd-EOB-DTPA-enhanced magnetic resonance imaging in primary biliary cholangitis patients

Japanese Journal of Radiology
Dan HanWen He

Abstract

To evaluate the feasibility of utilizing gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) for the assessment of Child-Pugh class and for differentiating between patients with primary biliary cholangitis (PBC) and posthepatitic cirrhosis. 45 PBC patients and 45 posthepatitic cirrhosis patients were enrolled and Gd-EOB-DTPA-enhanced MRI was applied. The average relative signal enhancement (RE) of the liver and average contrast to noise ratio (CNR) of common bile duct at 4, 20, and 50 min between different Child-Pugh classes of PBC patients were compared. The RE and CNR in all timepoints in patients with the same Child-Pugh class were compared between PBC patients and posthepatitic cirrhosis patients. The RE of liver and CNR of common bile duct at 4, 20, and 50 min was significantly different between all Child-Pugh classes of PBC patients. There were also no significant differences in the RE of liver and CNR of common bile duct in all timepoints between patients with PBC and posthepatitic cirrhosis in the same Child-Pugh class. Gd-EOB-DTPA-enhanced MRI is feasible for liver function assessment in PBC patients. However, the ability of this modality in differentiatin...Continue Reading

References

Sep 18, 1999·Digestive Diseases and Sciences·J ShimizuM Monden
Mar 25, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·E J Heathcote
Feb 15, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·L M Forman, M R Lucey
Dec 31, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Teh-Ia HuoShou-Dong Lee
Jun 6, 2008·World Journal of Gastroenterology : WJG·Andrea CrosignaniMauro Podda
May 1, 2009·Journal of Gastroenterology·Masato NaritaShinji Uemoto
May 2, 2009·Magnetic Resonance Imaging Clinics of North America·Richard Kinh Gian DoBachir Taouli
Jun 26, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Keith D LindorUNKNOWN American Association for Study of Liver Diseases
Nov 26, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Wilmar de GraafThomas M van Gulik
Oct 5, 2010·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Henrik NilssonEduard Jonas
Oct 20, 2010·Best Practice & Research. Clinical Gastroenterology·Douglas L NguyenKonstantinos N Lazaridis
Feb 24, 2011·Investigative Radiology·Takashi KatsubeTakamichi Murakami
May 3, 2011·Lancet·Carlo SelmiRoss L Coppel
Oct 15, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Mark D GoodwinDamien L Stella
Jun 1, 2012·Journal of Magnetic Resonance Imaging : JMRI·Nam Kyung LeeDae Hwan Kang
Nov 28, 2012·World Journal of Gastroenterology : WJG·Akihiro TateyamaMasayuki Nakajo
Oct 10, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Henrik NilssonEduard Jonas
May 9, 2015·World Journal of Hepatology·Treta Purohit, Mitchell S Cappell
Dec 18, 2015·Seminars in Liver Disease·Aliya F GulamhuseinKonstantinos N Lazaridis
Oct 26, 2016·European Journal of Radiology·Yoshifumi NodaKyongtae T Bae

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.