[Liver biopsy at the intersection of clinical and pathological diagnosis].

Der Pathologe
U Spengler, H-P Fischer

Abstract

Liver biopsy plays an important role in the diagnosis of liver diseases. Nowadays, biochemical, immunological, functional and molecular tests allow the etiology of many liver diseases to be clarified. The liver biopsy contributes essential information about the stage and grade of inflammatory liver diseases on the basis of consensus criteria. These data influence treatment and help to assess the prognosis. In addition, the different patterns of fibrosis allow conclusions about the cause and progress of the underlying liver disease. Hepatitis C, autoimmune hepatitis, unexplained severe course of hepatitis B, differentiation of simple steatosis from steatohepatitis, the differential diagnosis of cholestatic diseases, unclear hepatopathy, transplant pathology and last but not least, hepatic masses are the focal points of liver biopsy diagnoses. Increased risk of hemorrhage due to coagulation defects can be minimized by a transjugular biopsy. Liver masses can be effectively located and identified by radiologically or ultrasound-guided biopsy. Regular periodic conferences between clinicians and pathologists help to clarify individual problematic cases and will promote the diagnostic competence of both partners in hepatology.

References

Dec 1, 1988·Journal of Clinical Gastroenterology·N J TalleyV Hench
Dec 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M R TeliC P Day
Jan 15, 1993·Annals of Internal Medicine·C H Janes, K D Lindor
Jan 1, 1996·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·Y C WangS Z Lin
Feb 1, 1996·European Journal of Gastroenterology & Hepatology·A J StanleyP C Hayes
Mar 20, 1997·The New England Journal of Medicine·A MorenoC González
Mar 21, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P MathurinT Poynard
Aug 8, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A R CrawfordJ M Crawford
May 29, 1999·Gastroenterology·C A MatteoniA J McCullough
Jun 26, 1999·Annals of Internal Medicine·B R BaconR K Wolff
Jul 1, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·V Di MarcoA Craxì
Oct 26, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M M JamalD E Johnston
Jul 11, 2000·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·T PoynardP Bedossa
Aug 29, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J F CadranelF Degos
Dec 7, 2000·The New England Journal of Medicine·S ZeuzemM J Brunda
Dec 22, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S SaadehK Easley
Feb 15, 2001·The New England Journal of Medicine·A A BravoS Chopra
Apr 12, 2001·Seminars in Liver Disease·E M Brunt
May 9, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A S TavillUNKNOWN American Gastroenterological Association
Oct 27, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M Martinot-PeignouxP Marcellin
Nov 15, 2001·BMC Gastroenterology·C SpycherJ Reichen
Aug 29, 2002·Gastroenterology·Sherif SaadehMichael J Sheridan
Oct 19, 2002·The American Journal of Gastroenterology·Arie RegevEugene R Schiff
Apr 30, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Brent A Neuschwander-Tetri, Stephen H Caldwell
Jun 18, 2003·The American Journal of Gastroenterology·Kelly W BurakKeith D Lindor
Jul 23, 2003·The American Journal of Gastroenterology·Ioannis KyrlagkitsisMatthew E Cramp
Dec 4, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Pierre BedossaValerie Paradis
Apr 16, 2004·Seminars in Liver Disease·Maria Guido, Massimo Rugge
Nov 30, 2005·Seminars in Liver Disease·Antonello Pietrangelo
Jan 5, 2006·JAMA : the Journal of the American Medical Association·Chien-Jen ChenUNKNOWN REVEAL-HBV Study Group
Mar 15, 2006·Gastroenterology·Uchenna H IloejeUNKNOWN Risk Evaluation of Viral Load Elevation and Associated Liver Disease/Cancer-In HBV (the REVEAL-HBV) Study Group

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