PMID: 9428140Jan 1, 1997Paper

Liver hemostasis using high-intensity focused ultrasound

Ultrasound in Medicine & Biology
S VaezyL A Crum

Abstract

Liver hemorrhage, the major cause of death in hepatic trauma, is notoriously difficult to control. We report on the use of high-intensity focused ultrasound (HIFU) to arrest the bleeding from incisions made in rabbit livers. A HIFU transducer, with a spherically curved aperture of 6.34 cm2 area, a focal length of 4 cm and a frequency of 3.3 MHz was used. In approximately 94% of the incisions, the hemorrhage was reduced to a slow oozing of blood in less than 2 min. The maximum temperature of liver tissue around the incision area, during HIFU application, was measured to be 86 degrees C. The mechanism of hemostasis, confirmed by histological examination, appears to be coagulative necrosis of a volume of liver tissue around the incision. We believe that acoustic hemostasis, with the unique characteristic of "volume cauterization," offers a novel method for the management of liver hemorrhage and, thus, has major clinical implications.

References

Jan 1, 1995·Ultrasound in Medicine & Biology·C Delon-MartinD Cathignol
Mar 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F PratD Cathignol
Jan 1, 1993·Ultrasound in Medicine & Biology·C Damianou, K Hynynen
Mar 1, 1994·The Journal of the Acoustical Society of America·C Damianou, K Hynynen
Jan 1, 1993·Ultrasound in Medicine & Biology·L ChenJ P Bensted
Jul 1, 1995·International Journal of Urology : Official Journal of the Japanese Urological Association·T UchidaO Yoshida
Jan 1, 1996·Ultrasound in Medicine & Biology·K HynynenF A Jolesz
Jan 1, 1996·Ultrasound in Medicine & Biology·X Fan, K Hynynen
Jan 1, 1996·Ultrasound in Medicine & Biology·N A WatkinI Rivens
Jan 1, 1995·Ultrasound in Medicine & Biology·G ter Haar
Jan 1, 1996·Ultrasound in Medicine & Biology·A L Malcolm, G R ter Haar
Jan 1, 1996·Ultrasound in Medicine & Biology·H H Holm, B Skjoldbye
Jan 1, 1996·Ultrasound in Medicine & Biology·K HynynenF Jolesz
Sep 16, 1955·Science·W J FRYJ F BRENNAN
Nov 20, 1942·The Journal of General Physiology·J G LynnA E Miller

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Citations

Mar 29, 2012·Cardiovascular and Interventional Radiology·Gina K HesleyDavid A Woodrum
Aug 19, 2005·Current Treatment Options in Oncology·Michael O Koch, Thomas A Gardner
Mar 5, 2004·Ultrasound in Medicine & Biology·Sandra L PoliachikLawrence A Crum
May 5, 2000·Ultrasound in Medicine & Biology·G ter Haar
Oct 13, 2001·Ultrasound in Medicine & Biology·X ShiL A Crum
Dec 26, 2001·Ultrasound in Medicine & Biology·S L PoliachikL A Crum
Sep 18, 1998·Ultrasound in Medicine & Biology·S VaezyL Crum
Aug 26, 1999·Ultrasound in Medicine & Biology·R W MartinL Crum
Aug 26, 1999·Ultrasound in Medicine & Biology·S L PoliachikL A Crum
Feb 12, 2004·Seminars in Hematology·Michael A SilvaDarius F Mirza
Jul 8, 2005·Human Gene Therapy·Carol H MiaoLawrence A Crum
Jul 31, 2004·The Journal of Trauma·Carol J CornejoRoy W Martin
Jan 16, 2013·PloS One·Yossi MandelOfer Barnea
Aug 10, 2013·The Journal of the Acoustical Society of America·Yufeng Zhou, Xiaobin Wilson Gao
Apr 1, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·G ter Haar
Apr 1, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·S VaezyL Crum
Sep 23, 2003·The British Journal of Radiology·J E KennedyD Cranston
Feb 27, 2015·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·David E Goertz
Mar 21, 2015·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Meaghan A O'Reilly, Kullervo Hynynen
Apr 24, 2012·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Zhiqiu WangGuangxi Han
Jul 27, 2010·Ultrasonics·Kelsey J Carvell, Timothy A Bigelow
Aug 25, 2009·Ultrasound in Medicine & Biology·Ajay Anand, Peter J Kaczkowski
May 3, 2008·Ultrasound in Medicine & Biology·Ajay Anand, Peter J Kaczkowski
Nov 28, 2007·Muscle & Nerve·Jessica L FoleyShahram Vaezy
Sep 26, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G Ter Haar
Oct 7, 2015·Interface Focus·Christopher Earls Brennen
Jul 12, 2001·Annual Review of Biomedical Engineering·S VaezyL Crum
Feb 29, 2000·American Journal of Obstetrics and Gynecology·M L DenbowG R ter Haar
Feb 15, 2011·Ultrasound in Medicine & Biology·Cecille Pemberton Labuda, Charles C Church
Mar 9, 1999·Journal of Vascular Surgery·S VaezyL Crum
Jul 3, 2003·Gastrointestinal Endoscopy·Joo Ha HwangMichael B Kimmey
May 23, 2001·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·M D BrentnallL Crum
Nov 12, 2003·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Roy W MartinLawrence A Crum
Feb 28, 2002·The Journal of the Acoustical Society of America·Xuegong ShiLawrence A Crum
Jan 22, 2005·The Journal of the Acoustical Society of America·Xinmai YangR Glynn Holt

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