Liver Imaging Reporting and Data System:: Substantial Discordance Between CT and MR for Imaging Classification of Hepatic Nodules

Academic Radiology
Yu-Dong ZhangHai-Bin Shi

Abstract

The Liver Imaging Reporting and Data System (LI-RADS) is a newly developed nomogram for standardizing the performance and interpretation of liver imaging. However, it is unclear which imaging technique is optimal to exactly define LI-RADS scale. This study aims to determine the concordance of computed tomography (CT) and magnetic resonance imaging (MRI) for the classification of hepatic nodules (HNs) using a LI-RADS scoring system. Major imaging features (arterial hyper-enhancement, washout, pseudo-capsule, diameter, and tumor embolus) on CT versus MRI for 118 HNs in 84 patients with diffuse liver disease were rated independently using LI-RADS by two groups of readers. Inter-reader agreement (IRA) and intraclass agreement was determined by Fleiss and Cohen's kappa (κ). Logistic regression for correlated data was used to compare diagnostic ability. IRA was perfect for determination of nodule size and tumor embolus (κ = 0.94-0.98). IRA was moderate to substantial for determination of arterial hyper-enhancement, washout, and pseudo-capsule (κ = 0.54-0.72). Intraclass agreement between CT and MRI was substantial for determination of washout (0.632 [95% CI: 0.494, 0.771]) and pseudo-capsule (0.670 [95% CI: 0.494, 0.847]), and fair f...Continue Reading

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Citations

Sep 30, 2016·BMC Cancer·Roman KloecknerChristoph Düber
Mar 30, 2017·Abdominal Radiology·Victoria ChernyakClaude B Sirlin
Jun 20, 2019·Journal of Magnetic Resonance Imaging : JMRI·Khaled M ElsayesClaude B Sirlin
Feb 28, 2019·European Radiology·Cheng William HongClaude B Sirlin
May 4, 2017·Infectious Agents and Cancer·Vincenza GranataAntonella Petrillo
Oct 15, 2020·AJR. American Journal of Roentgenology·Robert M MarksVictoria Chernyak
Jun 3, 2021·Biology·Cosmin CaraianiChristoph Dietrich

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