Liver Resection for De Novo Hepatocellular Carcinoma Complicated by Pyogenic Liver Abscess: A Clinical Challenge

World Journal of Surgery
Kenneth S H ChokChung Mau Lo

Abstract

De novo hepatocellular carcinoma (HCC) complicated by pyogenic liver abscess is rare, and the standard of care for this disease has yet been defined. This study assesses whether liver resection can be recommended as its standard treatment. This retrospective study reviewed the prospectively collected data of the 1725 patients who underwent primary liver resection for HCC at our hospital during the period from December 1989 to December 2012. Outcomes were compared between patients with and without liver abscess. Twenty-two (1.28 %) patients had HCC and liver abscess. Fourteen of them received preoperative drainage. Patients with and without abscess had similar tumor characteristics, but patients with abscess had more operative blood loss (2.2 vs. 0.8 L; p < 0.0001) and more of them needed blood transfusion (63.6 vs. 23.1 %; p < 0.0001). They also had a longer hospital stay (38.5 vs. 10 days; p < 0.0001), a higher hospital mortality (40.9 vs. 2.8 %; p < 0.001), a higher postoperative complication rate (100 vs. 25.9 %; p < 0.0001), and poorer 1, 3, and 5-years disease-free survival rates (p = 0.023). The post-resection mortality of the patients with de novo HCC complicated by pyogenic liver abscess was so high that liver resection...Continue Reading

References

Apr 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K OkudaK Kohno
Dec 1, 1990·Annals of Surgery·G D BranumW C Meyers
Aug 1, 1973·The British Journal of Surgery·R N PughR Williams
Mar 11, 1999·The New England Journal of Medicine·H B El-Serag, A C Mason
Mar 17, 1999·Annals of Surgery·S T FanJ Wong
Jun 11, 1999·Annals of Surgery·Y FongL H Blumgart
Mar 13, 2009·European Journal of Gastroenterology & Hepatology·Susana OquiñenaBruno Sangro
Sep 22, 2009·The Kaohsiung Journal of Medical Sciences·Ching-I HuangWan-Long Chuang
Jun 21, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Tan To CheungSheung Tat Fan
Jun 14, 2014·Case Reports in Gastroenterology·Takahiro TominoYoshihiko Maehara

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Related Papers

Anales de medicina interna : organo oficial de la Sociedad Española de Medicina Interna
J L Ruiz-Rivas HernandoP Ferriz Moreno
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association
C T ChiuY F Liaw
© 2021 Meta ULC. All rights reserved