Liver Resection for Primary Intrahepatic Stones: Focus on Postoperative Infectious Complications

World Journal of Surgery
Gennaro ClementeFelice Giuliante

Abstract

Primary intrahepatic lithiasis is defined by the presence of gallstones at the level of cystic dilatations of the intrahepatic biliary tree. Liver resection is considered the treatment of choice, with the purpose of removing stones and atrophic parenchyma, also reducing the risk of cholangiocarcinoma. However, in consequence of the considerable incidence of infectious complications, postoperative morbidity remains high. The current study was designed to evaluate the impact of preoperative bacterial colonization of the bile ducts on postoperative outcome. The clinical records of 73 patients treated with liver resection were reviewed and clinical data, operative procedures, results of bile cultures, and postoperative outcomes were examined. Left hepatectomy (38 patients) and left lateral sectionectomy (19 patients) were the most frequently performed procedures. Overall morbidity was 38.3 %. A total of 133 microorganisms were isolated from bile. Multivariate analysis identified previous endoscopic or percutaneous cholangiography (p = 0.043) and preoperative cholangitis (p = 0.003) as the only two independent risk factors for postoperative infectious complications. Postoperative morbidity was strictly related to the preoperative bi...Continue Reading

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Citations

Oct 22, 2016·World Journal of Surgery·Ze-Wu MengYan-Ling Chen
Dec 21, 2019·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Orlando Jorge Martins TorresAntonio Nocchi Kalil
Feb 7, 2017·Gastroenterology Research and Practice·Xi RanBaojin Ma
Dec 17, 2020·Asian Journal of Surgery·Orlando Jorge M TorresPaulo Herman

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