Liver transplantation for biliary atresia: A single-center study from mainland China

World Journal of Gastroenterology : WJG
Qi-Gen LiQiang Xia

Abstract

To summarize our single-center experience with liver transplantation (LT) for biliary atresia (BA). From October 2006 to December 2012, 188 children with BA were analyzed retrospectively. The stage I group (from October 2006 to December 2010) comprised the first 74 patients, and the stage II group (from January 2011 to December 2012) comprised the remaining 114 patients. Finally, 123 liver transplants were performed in 122 (64.9%) patients, whereas 66 patients did not undergo LT due to denial by their parents or lack of suitable liver grafts. The selection of graft types depended on the patients' clinical status and whether a suitable living donor was available. The characteristics of patients in stages I and II were described, and the surgical outcomes of LT recipients were compared between the two stages. The Kaplan-Meier method was used to estimate the cumulative patient and graft survival rates, and the equality of survival distributions was evaluated using the log-rank test. The 188 children consisted of 102 boys and 86 girls. Their ages ranged from 3 to 144 mo with a median of 8 mo. One hundred and fifteen (61.2%) patients were born in rural areas. Comparing stage I and stage II patients, the proportion of patients referr...Continue Reading

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Citations

Jan 13, 2018·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mingxuan FengQiang Xia
Mar 21, 2020·Chinese Medical Journal·Bing-Yi ShiTao Yu
Jul 12, 2017·Gastroenterology Research and Practice·Rui DongShan Zheng

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