Liver/spleen volume ratio as a predictor of prognosis in primary biliary cirrhosis.

Journal of Gastroenterology
Yosuke MurataMorikazu Onji

Abstract

The course of primary biliary cirrhosis (PBC) is determined by clinical symptoms and histological findings. The present study examined the prognostic importance of imaging parameters in PBC. The volumes of the liver and spleen of patients with PBC were assessed by computed tomography (CT). The volume ratio of liver to spleen (LV/SV ratio) was evaluated and used for further analyses. The prognosis was significantly poorer in PBC patients with a low, rather than high, LV/SV ratio. The Cox proportional hazard regression model showed that the serum bilirubin level and the LV/SV ratio could predict the prognosis of PBC patients. In addition, the LV/SV ratio was significantly lower in patients who developed symptoms (s-PBC) than in those who remained asymptomatic (a-PBC) during the observation period. The LV/SV ratio is of prognostic importance in patients with PBC.

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Citations

Jul 15, 2009·World Journal of Gastroenterology : WJG·Peng LiuLi-Qin Zhao
Apr 20, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Peter JarcuskaLubomír Skladaný
Jan 26, 2013·Journal of Magnetic Resonance Imaging : JMRI·Xiao-li ChenChun-ping Li
Sep 27, 2012·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Raivo UiboM Eric Gershwin
Aug 16, 2016·IEEE Transactions on Visualization and Computer Graphics·Ievgeniia GutenkoMatthew A Barish
Feb 23, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Devika KapuriaTheo Heller
Apr 27, 2020·Journal of Assisted Reproduction and Genetics·Guruprasad NayakGuruprasad Kalthur
Jul 18, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yura AhnHo Sung Kim
Dec 7, 2020·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Katharina WöranBernhard Scheiner
May 6, 2021·The American Journal of the Medical Sciences·Milan PatelSuthat Liangpunsakul
Jul 9, 2021·The British Journal of Radiology·Sarah Pötter-LangMichael Trauner

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