Living donor kidney transplantation from the elderly donor

Transplantation Proceedings
H H WoltersJ G Brockmann

Abstract

The organ shortage has led to increasing acceptance of living donation in all transplant centers. Although the risk of impaired long-term outcome seems to be greater using elderly donors, these organs are not generally refused for transplantation. We report our experience with 25 living donor kidney transplantations from donors older than 60 years. Between 1995 and 2004, 124 living donor procedures were performed in our center from 83 related and 41 unrelated donors. Twenty-five donors (19 female, 6 male) were 60 years or older (mean, 65.3 +/- 3.9 years). The recipient included (10 females and 15 males) showed a higher degree of variance in age (46.1 +/- 14.6 years). The immunosuppressive protocol was cyclosporine (CyA)-based regimen in related cases and tacrolimus-based in unrelated cases. We transplanted 16 left and 9 right kidneys from older donors. The mean cold ischemia time was 171 +/- 64 minutes with a second warm ischemia time of 24 +/- 6 minutes. Severe arteriosclerosis made vascular reconstruction by graft interposition necessary in two recipients. The acute rejection rate was 20%. Two patients (8%) required dialysis in the early postoperative course, whereas initial function was excellent in 22 patients (88%). The me...Continue Reading

References

Apr 1, 1991·Transplant International : Official Journal of the European Society for Organ Transplantation·P FauchaldA Flatmark
May 1, 1985·Clinical Radiology·J S TapsonD N Kerr
Nov 14, 1997·Transplantation·E M JohnsonA J Matas
Jan 1, 1998·Transplantation Proceedings·B Cohen, G G Persijn

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Citations

Jul 26, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jagbir GillMichael Cecka
May 23, 2009·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Y IordanousUNKNOWN Donor Nephrectomy Outcomes Research (DONOR) Network
Dec 1, 2011·Arab Journal of Urology·Ahmed I KamalAhmed A Shokeir

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