Living donor liver transplantation: a life-saving option in emergency situations for diffuse hepatic neuroendocrine tumor metastasis

Transplantation Proceedings
Y YankolM Kalayoglu

Abstract

Liver metastasis is the main cause of death in patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs), but only 10%-20% of metastasis in these cases is resectable at the time of diagnosis. In some cases, medical and interventional radiological treatments may not be effective. Liver transplantation, although controversial, may be an option. Worldwide organ-sharing systems do not provide exception points, but give recommendations for liver transplantation in cases of hepatic metastasis from GEP-NETs due to the issue of fair access to donor organs. Living donor liver transplantation is an option in select cases. Presented here are 2 cases in which living donor liver transplantation was performed in emergency situations as a life-saving procedure, with acceptable survival and without donor complications.

References

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Jun 21, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James C YaoDouglas B Evans
May 19, 2010·Transplant International : Official Journal of the European Society for Organ Transplantation·Eliano Bonaccorsi-RianiJan Lerut
Aug 3, 2010·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Eric J Grossman, J Michael Millis
Apr 18, 2013·Pancreas·Pamela L KunzUNKNOWN North American Neuroendocrine Tumor Society
May 17, 2014·World Journal of Gastroenterology : WJG·Christina HacklMartin Loss

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