Lobar and segmental liver atrophy associated with hilar cholangiocarcinoma and the impact of hilar biliary anatomical variants: a pictorial essay.

Insights Into Imaging
Brendon R FriesenNeil A Collier

Abstract

The radiological features of lobar and segmental liver atrophy and compensatory hypertrophy associated with biliary obstruction are important to recognise for diagnostic and therapeutic reasons. Atrophied lobes/segments reduce in volume and usually contain crowded dilated bile ducts extending close to the liver surface. There is often a "step" in the liver contour between the atrophied and non-atrophied parts. Hypertrophied right lobe or segments enlarge and show a prominently convex or "bulbous" visceral surface. The atrophied liver parenchyma may show lower attenuation on pre-contrast computed tomography (CT) and CT intravenous cholangiography (CT-IVC) and lower signal intensity on T1-weighted magnetic resonance imaging (MRI). Hilar biliary anatomical variants can have an impact on the patterns of lobar/segmental atrophy, as the cause of obstruction (e.g. cholangiocarcinoma) often commences in one branch, leading to atrophy in that drainage region before progressing to complete biliary obstruction and jaundice. Such variants are common and can result in unusual but explainable patterns of atrophy and hypertrophy. Examples of changes seen with and without hilar variants are presented that illustrate the radiological features o...Continue Reading

References

Jan 1, 1992·Gastrointestinal Radiology·Y YamashitaS Wallace
Jul 1, 1990·World Journal of Surgery·J M Ham
Apr 1, 1989·American Journal of Surgery·N S HadjisL H Blumgart
Mar 1, 1989·Journal of Computer Assisted Tomography·P DemaerelA L Baert
Jul 1, 1981·AJR. American Journal of Roentgenology·M R MyracleP Matin
Nov 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S KawasakiH Kawarazaki
Oct 1, 1996·AJR. American Journal of Roentgenology·L E HannL H Blumgart
Jan 1, 1997·Clinical Imaging·E S SiegelmanD G Mitchell
Mar 28, 1998·Abdominal Imaging·H IshidaO Masamune
Jul 9, 2002·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A HumarW D Payne
Aug 10, 2004·Surgical and Radiologic Anatomy : SRA·J R Ortale, L C Borges Keiralla

❮ Previous
Next ❯

Citations

Feb 25, 2014·Surgical Oncology Clinics of North America·Victor M ZaydfudimDavid M Nagorney
May 31, 2017·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Christoph SchrammUNKNOWN MRI working group of the IPSCSG
Oct 24, 2018·Radiology·Baljendra S KapoorJonathan M Lorenz
Feb 24, 2019·Clinical Journal of Gastroenterology·Takahiro ZendaTatsuo Nakano
May 1, 2017·Abdominal Radiology·Ishan GargSudhakar K Venkatesh
May 5, 2018·Expert Review of Anticancer Therapy·Charles W KimbroughTimothy M Pawlik
Oct 1, 2016·Insights Into Imaging·Gary Xia Vern TanTom Sutherland
Jul 15, 2021·Journal of Pediatric Gastroenterology and Nutrition·Juliana C C BarretoMaria Angela Bellomo-Brandão

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Koray KarabulutOrhan Arioğul
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Sarwa Darwish MuradJulie K Heimbach
© 2022 Meta ULC. All rights reserved