Local and systemic effects on blood lactate concentration during exercise with small and large muscle groups.

Pflügers Archiv : European journal of physiology
R ChudallaN Maassen

Abstract

To evaluate the relationship between lactate release and [lac](art) and to investigate the influence of the catecholamines on the lactate release, 14 healthy men [age 25+/-3 (SE) year] were studied by superimposing cycle on forearm exercise, both at 65% of their maximal power reached in respective incremental tests. Handgrip exercise was performed for 30 min at 65% of peak power. In addition, between the tenth and the 22nd minute, cycling with the same intensity was superimposed. The increase in venous lactate concentration ([lac](ven)) (rest: 1.3+/-0.4 mmol.l(-1); 3rd min: 3.9+/-0.8 mmol.l(-1)) begins with the forearm exercise, whereas arterial lactate concentration ([lac](art)) remains almost unchanged. Once cycling has been added to forearm exercise (COMB), [lac](art) increases with a concomitant increase in [lac](ven) (12th min: [lac](art), 3.2+/-1.3 mmol.l(-1); [lac](ven), 5.7+/-2.2 mmol.l(-1)). A correlation between oxygen tension (P(v)O(2)) and [lac](ven) cannot be detected. There is a significant correlation between [lac](art) and norepinephrine ([NE]) (y=0.25x+1.2; r=0.815; p<0.01) but no correlation between lactate release and epinephrine ([EPI]) at moderate intensity. Our main conclusion is that lactate release from ...Continue Reading

References

Mar 1, 1976·Acta Physiologica Scandinavica·B SaltinD Gollnick
Jul 1, 1977·Physiological Reviews·A D Macknight, A Leaf
Jul 1, 1991·Journal of Applied Physiology·G A BrooksJ T Reeves
Dec 1, 1990·Medicine and Science in Sports and Exercise·S P HookerN Martin
May 1, 1989·Clinical Science·K N FraynP L Whyte
Jan 1, 1989·European Journal of Applied Physiology and Occupational Physiology·N Maassen, M W Busse
Oct 1, 1989·Journal of Applied Physiology·R S Mazzeo, P Marshall
Oct 1, 1986·Clinical Physiology·O J HartlingJ Trap-Jensen
Mar 1, 1986·The Journal of Clinical Investigation·G AhlborgP Felig
Apr 1, 1986·Journal of Applied Physiology·J RaynaudJ Durand
Apr 1, 1985·International Journal of Sports Medicine·M LehmannJ Keul
Dec 1, 1985·Journal of Applied Physiology·W N StainsbyP D Eitzman
Jan 1, 1972·Journal of Applied Physiology·H V ForsterG A DoPico
Aug 1, 1970·Scandinavian Journal of Clinical and Laboratory Investigation·L Jorfeldt, J Wahren
Aug 1, 1984·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·W N StainsbyG M Andrew
Jan 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·B J WhippK Wasserman
Aug 1, 1981·International Journal of Sports Medicine·H StegmannA Schnabel
Nov 15, 1981·The Biochemical Journal·A C Bylund-FelleniusT Scherstén
Jan 1, 1994·European Journal of Applied Physiology and Occupational Physiology·J de BoerJ Korf
Nov 1, 1993·Acta Physiologica Scandinavica·L GullestadO M Sejersted
Jun 1, 1993·Journal of Applied Physiology·M Jensen-UrstadK Sahlin
Jan 1, 1996·The American Journal of Physiology·B IllekT E Machen
Dec 10, 1997·International Journal of Sports Medicine·N Maassen, G Schneider
Apr 4, 1998·Medicine and Science in Sports and Exercise·R M McAllister
Aug 4, 1998·Journal of Applied Physiology·R S RichardsonP D Wagner
Oct 7, 1998·Journal of Applied Physiology·B GrassiM C Hogan
Nov 24, 1999·Journal of Applied Physiology·B C BergmanG A Brooks
Apr 26, 2000·American Journal of Physiology. Endocrinology and Metabolism·S H KreismanE B Marliss
Jun 22, 2000·Medicine and Science in Sports and Exercise·R A WiswellD M Hyslop
Feb 27, 2001·Medicine and Science in Sports and Exercise·R M Nicholson, G G Sleivert
Dec 1, 1964·The American Journal of Cardiology·K WASSERMAN, M B MCILROY

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Citations

Feb 14, 2008·Journal of the International Society of Sports Nutrition·Ralf JägerNorbert Maassen
May 23, 2015·European Journal of Applied Physiology·Samuel J OliverNeil P Walsh
Mar 21, 2013·Nitric Oxide : Biology and Chemistry·Dimitrios TsikasNorbert Maassen
Dec 10, 2009·Medicine and Science in Sports and Exercise·E Victoria WiltshireMichael E Tschakovsky
Aug 4, 2007·Journal of Applied Physiology·Martin WhithamNeil P Walsh
Sep 29, 2007·Journal of Applied Physiology·Stewart J LaingNeil P Walsh
Mar 24, 2020·Hypertension·Natalie K JonesMatthew A Bailey
Apr 28, 2021·Journal of Manipulative and Physiological Therapeutics·Pooja BhatiM Ejaz Hussain

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