Local and systemic humoral immune response in farmed Atlantic salmon (Salmo salar L.) under a natural amoebic gill disease outbreak

Fish & Shellfish Immunology
Mar Marcos-LópezMaría A Esteban

Abstract

Amoebic gill disease (AGD), caused by the protozoan parasite Neoparamoeba perurans, is one of the most significant infectious diseases for Atlantic salmon (Salmo salar L.) mariculture. The present study investigated the humoral immune response (both local in gill mucus and systemic in serum) of farmed Atlantic salmon naturally infected with N. perurans in commercial sea pens, at two different stages of the disease and after freshwater treatment. Parameters analysed included activity of immune related enzymes (i.e. lysozyme, peroxidase, protease, anti-protease, esterase, alkaline phosphatase), IgM levels, and the terminal carbohydrate profile in the gill mucus. Overall, greater variations between groups were noted in the immune parameters determined in gill mucus than the equivalent in the serum. In gill mucus, IgM levels and peroxidase, lysozyme, esterase and protease activities were decreased in fish showing longer exposure time to the infection and higher disease severity, then showed a sequential increase after treatment. Results obtained highlight the capacity of gills to elicit a local response to the infection, indicate an impaired immune response at the later stages of the disease, and show partial reestablishment of the...Continue Reading

Citations

Jun 18, 2019·Journal of Fish Diseases·Ottavia BenedicentiChristopher J Secombes
Jun 22, 2020·Parasite Immunology·Mar Marcos-López, Hamish D Rodger
Apr 1, 2021·Developmental and Comparative Immunology·Irene SalinasJ Oriol Sunyer
Jul 3, 2021·Microorganisms·Kerrie Ní DhufaighOrla Slattery

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