PMID: 8941976Sep 1, 1996Paper

Local antibody production in the oviduct and gut of hens infected with a variant strain of infectious bronchitis virus

Veterinary Immunology and Immunopathology
G D Raj, R C Jones

Abstract

Following infection of 16-week old specific pathogen-free (SPF) female chickens with an enterotropic variant of infectious bronchitis virus (IBV) strain G, IBV-specific Immunoglobulin G (IgG) and IgA were detected in tears, tracheal washes, oviduct washes, duodenal and caecal contents using class-specific monoclonal antibodies in enzyme linked immunosorbent assays (ELISA). IgG antibody content was highest in tears on Day 7 post-infection (p.i.) and was still detectable on Day 23 p.i. Significant levels of IgG antibody were present in oviduct washes on Days 7 and 23 p.i. Tears showed the highest IgA antibody concentration of any sample on Day 7 p.i. but this decreased to an insignificant level by Day 17 p.i. Oviduct and tracheal washes had IgA antibodies on Day 7 p.i. Significant levels of both antibody classes were detected in duodenal contents on Day 17 p.i. only but neither was present in caecal contents. Using a method which compares titre of antibody produced from pieces of tissue at 4 degrees C with that at 37 degrees C as an indicator of local secretion, IgG and IgA antibody synthesis was demonstrated in the Harderian gland on Days 7 and 17 p.i. Local IgG antibody synthesis was seen in the oviduct on Day 7 p.i. but on Day...Continue Reading

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Citations

May 25, 2005·Veterinary Immunology and Immunopathology·Silke Rautenschlein, Christine Haase
Sep 17, 2005·Animal Health Research Reviews·Chang-Won Lee, David L Suarez
Jun 24, 2008·Avian Pathology : Journal of the W.V.P.A·Francisco PerozoLinda B Purvis
May 17, 2008·Avian Pathology : Journal of the W.V.P.A·G D Raj, R C Jones
Oct 19, 2010·Research in Veterinary Science·Sanganagouda KoppadV Thiagarajan
Aug 25, 2015·Viral Immunology·Rajesh ChhabraKannan Ganapathy
Jan 15, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Nicole Assis PereiraLeonardo José Richtzenhain

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