Abstract
Atrial fibrillation (AF) is considered to be maintained by multiple reentrant circuits without or with a very short excitable gap. However, the possibility of local atrial capture has been shown recently in experimental AF or induced AF in humans. This study was undertaken to evaluate the feasibility of atrial capture-suggestive of an excitable gap-in spontaneous chronic AF. Decremental pacing was performed in 47 right atrial sites in 14 patients with chronic AF, not taking antiarrhythmic drugs. A Franz catheter (for pacing and monophasic action potential recording) and a recording quadripolar catheter positioned about 10 mm apart were used. Local capture was achieved in 41 (87.2%) sites for a total of 100 captures. In 71 episodes the capture was lost within 15 seconds, while in the remaining 29, pacing was stopped after 15 seconds of stable capture. AF types immediately before capture were type 1 in 83 and type 2 in 17 episodes. Type 3 AF was never captured. Pacing cycle at capture was 175.7 +/- 20.9 ms. The baseline atrial interval (FF) was 185.4 +/- 24.5, significantly longer than the FF recorded during pacing immediately before capture (176.0 +/- 19.8 ms) (P < .02). During spontaneous chronic AF in humans, (1) local capture...Continue Reading
References
Oct 1, 1978·Pacing and Clinical Electrophysiology : PACE·J L WellsA L Waldo
Jul 1, 1977·Circulation Research·M A AllessieF J Schopman
Mar 1, 1993·Pacing and Clinical Electrophysiology : PACE·C F PieperA Pacifico
Jun 1, 1996·Journal of the American College of Cardiology·H LiM Akhtar
Citations
Feb 8, 2005·Basic Research in Cardiology·Paulus KirchhofLars Eckardt
Jul 10, 2010·Annals of Biomedical Engineering·Laurent UldryLukas Kappenberger
Jan 15, 2000·Journal of the American College of Cardiology·K ShinagawaS Ogawa
Aug 14, 2003·Pacing and Clinical Electrophysiology : PACE·Viveka FrykmanMarten Rosenqvist
Apr 21, 1999·Journal of Cardiovascular Electrophysiology·A CapucciG Q Villani
Jun 9, 2000·Annual Review of Physiology·S NattelL Yue
Mar 2, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Zhaoliang ShanYutang Wang
May 7, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Alexandru RusuNathalie Virag
Apr 15, 2005·Journal of Cardiovascular Electrophysiology·Kumaraswamy NanthakumarRaymond E Ideker
Oct 3, 2003·Journal of Cardiovascular Electrophysiology·Paulus KirchhofWilhelm Haverkamp
Mar 21, 2007·Pacing and Clinical Electrophysiology : PACE·Nikolay ShlevkovThorsten Lewalter
Aug 6, 2011·Journal of Cardiovascular Electrophysiology·Sevasti-Maria ChaldoupiPeter Loh
Jan 1, 2008·IEEE Reviews in Biomedical Engineering·Vincent JacquemetCraig S Henriquez
Mar 27, 2004·Physiological Reviews·André G Kléber, Yoram Rudy
Aug 2, 2000·Journal of Cardiovascular Electrophysiology·P KirchhofW Haverkamp
Dec 25, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Adrian LucaNathalie Virag
Jan 21, 2011·Physiological Reviews·Ulrich SchottenAndreas Goette
Jun 27, 2006·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michele GuliziaAndrea Grammatico